Pantethine is most commonly used for lowering levels of cholesterol and triglycerides in people with diabetes or high levels of lipoproteins in the blood (hyperlipoproteinemia).
How does it work ?
Uses & Effectiveness ?
Possibly Effective for
- High levels of lipoproteins in the blood (hyperlipoproteinemia). While not all research findings agree, taking pantethine by mouth or as a shot might slightly lower triglycerides, total cholesterol, and "bad" low-density lipoprotein (LDL) cholesterol; as well as raise "good" high-density lipoprotein (HDL) cholesterol. Pantethine also appears to correct blood fat problems that often occur in kidney failure patients who are undergoing hemodialysis.
Insufficient Evidence for
- Athletic performance. Some research suggests that taking pantethine in combination with pantothenic acid and thiamine (given as allithiamin) does not improve muscular strength or endurance in well-trained athletes.
- An inherited disease that can lead to kidney failure (cystinosis). Early research suggests that pantethine might be beneficial for cystinosis.
- Supporting adrenal function.
- Formaldehyde sensitivity.
- Other conditions.
When given as a shot: There isn't enough reliable information to know if pantethine is safe when given as a shot or what the side effects might be.
Special Precautions and Warnings
Bleeding disorders: There is some evidence that pantethine can slow blood clotting. Some healthcare providers worry that pantethine might increase the risk of severe bleeding in patients with bleeding disorders. If you have a bleeding disorder, talk to your healthcare provider before starting pantethine.
Surgery: Pantethine might slow blood clotting. There is a concern that it might increase the risk of extra bleeding during and after surgery. Stop using pantethine at least 2 weeks before a scheduled surgery.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with PANTETHINE
Pantethine might slow blood clotting. Taking pantethine along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Be cautious with this combination
- High levels of lipoproteins in the blood (hyperlipoproteinemia): 300 mg of pantethine 3 to 4 times daily.
- High levels of lipoproteins in the blood (hyperlipoproteinemia): 400 mg of pantethine daily.
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