SCHIZONEPETA

OTHER NAME(S):

Cataire Japonaise, Chataire Japonaise, Hairy Sage, Herba Schizonepetae, Hjonggae, Hyonggae, Japanese Catnip, Japanese Mint, Jing Jie, Jingjie, Keigai, Nepeta multifida, Nepeta tenuifolia, Schizonepetae Herba, Schizonepeta multifida, Schizonepeta Spica, Schizonepeta tenuifolia, Schizonepetae Herba, Tenuifolia, Trefliksnepeta.

Overview

Overview Information

Schizonepeta is a plant. The parts that grow above the ground are used to make medicine.

Schizonepeta is used for the common cold, fever, sore throat, pain, eczema (atopic dermatitis), psoriasis, and many other conditions, but there is no good scientific evidence to support these uses.

How does it work?

Schizonepeta contains chemicals that might reduce swelling and allergic reactions.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Eczema (atopic dermatitis). Some research shows that schizonepeta in combination with 9 other herbs (Zemaphyte, Phytopharm Plc.) might reduce redness and irritation in people with eczema. However, other research shows no effect.
  • Common cold.
  • Fever.
  • Sore throat.
  • Psoriasis.
  • Abnormally heavy bleeding during menstrual periods (menorrhagia).
  • Other conditions.
More evidence is needed to rate the effectiveness of schizonepeta for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: There isn't enough information to know if schizonepeta is safe or what the side effects might be. When taken at high doses, schizonepeta is POSSIBLY UNSAFE and might damage the liver.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if schizonepeta is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Liver disease: There is a concern that schizonepeta might make liver disease worse. Don't use it if you have a liver problem.

Interactions

Interactions?

We currently have no information for SCHIZONEPETA Interactions.

Dosing

Dosing

The appropriate dose of schizonepeta depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for schizonepeta. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Bao B, Geng T, Cao Y, et al. Effects of schizonepetin on activity of mRNA expression of cytochrome P450 enzymes in rats. Int J Mol Sci. 2012;13(12):17006-18. View abstract.
  • Choi YY, Kim MH, Kim JH, et al. Schizonepeta tenuifolia inhibits the development of atopic dermatitis in mice. Phytother Res. 2013;27(8):1131-5. View abstract.
  • Ding AW, Wu H, Kong LD, et al. [Research on hemostatic mechanism of extracts from carbonized Schizonepeta tenuifolia Brig]. Zhongguo Zhong Yao Za Zhi 1993;18:598-600, 638. View abstract.
  • Fung AY, Look PC, Chong LY, et al. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. Int J Dermatol 1999;38:387-92 . View abstract.
  • Fung D, Lau CB. Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applications. J Clin Pharmacol 2002;42:30-6. View abstract.
  • Kirby AJ, Schmidt RJ. The antioxidant activity of Chinese herbs for eczema and of placebo herbs--I. J Ethnopharmacol 1997;56:103-8. View abstract.
  • Lin R, Tian J, Huang G, et al. Analysis of menthol in three traditional Chinese medicinal herbs and their compound formulation by GC-MS. Biomed Chromatogr 2002;16:229-33. View abstract.
  • Liu HN, Jaw SK, Wong CK. Chinese herbs and atopic dermatitis. Lancet 1993;342:1175-6.
  • Shan MQ, Qian Y, Yu S, et al. Anti-inflammatory effect of volatile oil from Schizonepeta tenuifolia on carrageenin-induced pleurisy in rats and its application to study of appropriate harvesting time coupled with multi-attribute comprehensive index method. J Ethnopharmacol. 2016;194:580-6. View abstract.
  • Sheehan M, Rustin MHA, Atherton DJ, et al. Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis. Lancet 1992;340:13-17. View abstract.
  • Sheehan MP, Atherton DJ. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema. Br J Dermatol 1992;126:179-84. View abstract.
  • Sheehan MP, Atherton DJ. One-year follow-up of children treated with Chinese medicinal herbs for atopic eczema. Br J Dermatol. 1994;130:488-93. View abstract.
  • Sheehan MP, Stevens H, Ostlere LS, et al. Follow-up of adult patients with atopic eczema treated with Chinese herbal therapy for 1 year. Clin Exp Dermatol. 1995;20:136-40. View abstract.
  • Shin TY, Jeong HJ, Jun SM, et al. Effect of Schizonepeta tenuifolia extract on mast cell-mediated immediate-type hypersensitivity in rats. Immunopharmacol Immunotoxicol 1999;21:705-15. View abstract.
  • Tohda C, Kakihara Y, Komatsu K, Kuraishi Y. Inhibitory effects of methanol extracts of herbal medicines on substance P-induced itch-scratch response. Biol Pharm Bull 2000;23:599-601. View abstract.
  • Wang BS, Huang GJ, Tai HM, Huang MH. Antioxidant and anti-inflammatory activities of aqueous extracts of Schizonepeta tenuifolia Briq. Food Chem Toxicol. 2012;50(3-4):526-31. View abstract.
  • Zhang W, Leonard T, Bath-Hextall F, et al. Chinese herbal medicine for atopic eczema. Cochrane Database Syst Rev 2004;4:CD002291. View abstract.
  • Zhou S, Koh HL, Gao Y, et al. Herbal bioactivation: the good, the bad and the ugly. Life Sci 2004;74:935-68. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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