D-Mannoheptulose, Extracto de Azúcar de Aguacate, Extrait de Sucres d’Avocat, Mannoheptulose, Manno-heptulose, Séduheptulose.


Overview Information

Avocado sugar extract is a chemical taken from avocado fruit and used as medicine.

People take avocado sugar extract to lose weight.

How does it work?

Developing research suggests avocado sugar extract might block the effects of insulin and prevent the break down of sugar (glucose).


Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of avocado sugar extract for this use.

Side Effects

Side Effects & Safety

It is not known if avocado sugar extract is safe.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of avocado sugar extract during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Diabetes: There is concern that avocado sugar extract might make diabetes worse because it seems to block the effects of insulin. This reduces the amount of sugar that the body breaks down and increases blood sugar levels.

Surgery: Avocado sugar extract might affect bloodsugar levels. There is some concern that it might interfere with blood sugar control during and after surgery. Stop using avocado sugar extract at least 2 weeks before a scheduled surgery.



Moderate Interaction

Be cautious with this combination

  • Medications for diabetes (Antidiabetes drugs) interacts with AVOCADO SUGAR EXTRACT

    Avocado sugar extract might increase blood sugar. Diabetes medications are used to lower blood sugar. Taking avocado sugar extract along with diabetes medications might interfere with the blood sugar lowering effects of diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
    Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
    Before taking avocado sugar extract, talk with your healthcare professional if you take these or any other medications.



The appropriate dose of avocado sugar extract depends on several factors such as the user’s age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for avocado sugar extract. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • Graziani J, Levy J, Dimant E. An inhibitory effect of D-Mannoheptulose on lactate formation in human whole blood in vitro. FEBS Lett 1971;16:241-4. View abstract.
  • Ladriere L, Kadiata MM, Malaisse WJ. Comparison between the effects of D-mannoheptulose and its hexaacetate ester upon D-glucose metabolism in rat erythrocytes. Horm Metab Res 1998;30:244-5. View abstract.
  • Malaisse WJ, Doherty M, Kadiata MM, et al. Pancreatic fate of D-[3H] mannoheptulose. Cell Biochem Funct 2001;19:171-9. View abstract.
  • Rasschaert J, Kadiata MM, Malaisse WJ. Effects of D-mannoheptulose upon D-glucose metabolism in tumoral pancreatic islet cells. Mol Cell Biochem 2001;226:77-81. View abstract.
  • Sehlin J. Effect of mannoheptulose on the dynamics of glucose oxidation in the pancreatic beta-cells. FEBS Lett 1973;30:45-8. View abstract.
  • Shaw PE, Wilson CW 3rd, Knight RJ Jr. High-performance liquid chromatographic analysis of D-manno-heptulose, perseitol, glucose, and fructose in avocado cultivars. J Agric Food Chem 1980;28:379-62. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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