C. Fimbriate, Caraluma, Caralluma ascendens, Caralluma Cactus, Caralluma Extract, Caralluma fimbriata, Caralluma Fimbriata Extract, Caraluma Pregnane Glycosides, Extrait de Caralluma, Extrait de Caralluma Fimbriata, Kallimudayan, Karallamu, Kullee Mooliyan, Makad Shenguli, Ranshabar, Shindala Makadi, Wild Succulent Cactus, Yugmaphallottama.<br/><br/>
Overview InformationCaralluma is a (cactus) from India.
Some people take caralluma by mouth decrease appetite (hunger) in order to lose weight. It is also taken by mouth for a genetic disorder called Prader-Willi Syndrome. But there is currently limited scientific research to support these uses.
In India, caralluma is used in preserves such as chutneys and pickles.
How does it work?Chemicals contained in the caralluma plant are thought to decrease appetite.
Uses & Effectiveness
Insufficient Evidence for
- Prader-Willi syndrome. Some early research in children between the ages of 5-17 suggests that taking an extract of caralluma may help to decrease appetite.
- Weight loss. Some early research shows that taking an extract of caralluma may decrease food intake, feelings of hunger, and waist size. However, other research suggests it does not affect these things. Also, it does not seem to decrease weight, body mass index (BMI), body fat, or hip size.
- Quenching thirst.
- Increasing endurance.
- Other conditions.
Side Effects & SafetyCaralluma is LIKELY SAFE for most people when taken by mouth in amounts commonly found in foods. Caralluma is POSSIBLY SAFE when taken by mouth in medicinal amounts for up to 12 weeks. Caralluma might cause some mild side effects such as stomach upset, intestinal gas, constipation, and stomach pain. These side effects usually go away after a week of use.
Special Precautions & Warnings:Children: Caralluma is POSSIBLY SAFE when taken by mouth by children in medicinal amounts, short-term.
Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking CARALLUMA if you are pregnant or breast-feeding. Stay on the safe side and avoid use.
We currently have no information for CARALLUMA Interactions.
The appropriate dose of caralluma depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for caralluma. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
- Adnan M, Jan S, Mussarat S, et al. A review on ethnobotany, phytochemistry and pharmacology of plant genus Caralluma R. Br. J Pharm Pharmacol 2014;66(10):1351-68. View abstract.
- Arora E, Khajuria V, Tandon VR, et al. To evaluate efficacy and safety of Caralluma fimbriata in overweight and obese patients: a randomized, single blinded, placebo control trial. Perspect Clin Res 2015;6(1):39-44. View abstract.
- Concalves JL, Lopes RC, Oliveira DB, et al. In vitro anti-rotavirus activity of some medicinal plants used in Brazil against diarrhea. J Ethnopharmacol 2005;99(3):403-7. View abstract.
- Gencor Pacific, Inc. New dietary ingredient notification: Caralluma fimbriata extract: Volumes 1-3. Notification to U.S. Food and Drug Administration, August 25, 2004. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-rpt0252-05-Caralluma-Fimbriata-Extract-vol184.pdf.
- GRAS Notice 000500: Hydroethanolic extract of Caralluma Fimbriata. https://www.fda.gov/downloads/Food/IngredientsPackagingLabeling/GRAS/NoticeInventory/ucm402152.pdf. Accessed July 9, 2017.
- Griggs JL, Su XQ, Mathai ML. Caralluma fimbriata supplementation improves the appetite behavior of children and adolescents with Prader-Willi syndrome. N Am J Med Sci 2015;7(11):509-16. View abstract.
- Kuriyan R, Raj T, Srinivas SK, et al. Effect of Caralluma Fimbriata extract on appetite, food intake and anthropometry in adult Indian men and women. Appetite 2007;48:338-44. View abstract.
- Odendaal AY, Deshmukh NS, Marx TK, Schauss AG, Endres JR, Clewell AE. Safety assessment of a hydroethanolic extract of Caralluma fimbriata. Int J Toxicol 2013;32(5):385-94. View abstract.