CARALLUMA

OTHER NAME(S):

C. Fimbriate, Caraluma, Caralluma ascendens, Caralluma Cactus, Caralluma Extract, Caralluma fimbriata, Caralluma Fimbriata Extract, Caraluma Pregnane Glycosides, Extrait de Caralluma, Extrait de Caralluma Fimbriata, Kallimudayan, Karallamu, Kullee Mooliyan, Makad Shenguli, Ranshabar, Shindala Makadi, Wild Succulent Cactus, Yugmaphallottama.

Overview

Overview Information

Caralluma is a (cactus) from India.

People use caralluma to decrease appetite or hunger, especially during times of food shortages, for obesity, and for a rare, inherited disorder that causes obesity, short stature, and learning disability (Prader-Willi syndrome or PWS). There is no good scientific evidence to support these uses.

In India, caralluma is used in preserves such as chutneys and pickles.

How does it work?

Chemicals contained in the caralluma plant are thought to decrease appetite.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • A type of persistent anxiety marked by exaggerated worry and tension (generalized anxiety disorder or GAD). Early research shows that taking caralluma reduces anxiety and stress by a small amount in people with mild GAD.
  • Obesity. Some early research shows that taking an extract of caralluma may decrease food intake, feelings of hunger, and waist size. But not all research agrees. Also, it does not seem to decrease weight, body mass index (BMI), body fat, or hip size.
  • A rare, inherited disorder that causes obesity, short stature, and learning disability (Prader-Willi syndrome or PWS). Some early research suggests that taking an extract of caralluma may help to decrease appetite in children 5-17 years of age with PWS.
  • Quenching thirst.
  • Increasing endurance.
  • Pain.
  • Other conditions.
More evidence is needed to rate the effectiveness of caralluma for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Caralluma is LIKELY SAFE for most people when taken in amounts commonly found in foods. Caralluma is POSSIBLY SAFE when taken in medicinal amounts for up to 12 weeks. Caralluma might cause some mild side effects such as stomach upset, intestinal gas, constipation, and stomach pain. These side effects usually go away after about a week of use.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if caralluma is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions

Interactions?

We currently have no information for CARALLUMA Interactions.

Dosing

Dosing

The appropriate dose of caralluma depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for caralluma. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Adnan M, Jan S, Mussarat S, et al. A review on ethnobotany, phytochemistry and pharmacology of plant genus Caralluma R. Br. J Pharm Pharmacol 2014;66(10):1351-68. View abstract.
  • Arora E, Khajuria V, Tandon VR, et al. To evaluate efficacy and safety of Caralluma fimbriata in overweight and obese patients: a randomized, single blinded, placebo control trial. Perspect Clin Res 2015;6(1):39-44. View abstract.
  • Astell KJ, Mathai ML, McAinch AJ, Stathis CG, Su XQ. A pilot study investigating the effect of Caralluma fimbriata extract on the risk factors of metabolic syndrome in overweight and obese subjects: a randomised controlled clinical trial. Complement Ther Med. 2013;21(3):180-9. View abstract.
  • Concalves JL, Lopes RC, Oliveira DB, et al. In vitro anti-rotavirus activity of some medicinal plants used in Brazil against diarrhea. J Ethnopharmacol 2005;99(3):403-7. View abstract.
  • Gencor Pacific, Inc. New dietary ingredient notification: Caralluma fimbriata extract: Volumes 1-3. Notification to U.S. Food and Drug Administration, August 25, 2004. Available at: https://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-rpt0252-05-Caralluma-Fimbriata-Extract-vol184.pdf.
  • GRAS Notice 000500: Hydroethanolic extract of Caralluma Fimbriata. https://www.fda.gov/downloads/Food/IngredientsPackagingLabeling/GRAS/NoticeInventory/ucm402152.pdf. Accessed July 9, 2017.
  • Griggs JL, Su XQ, Mathai ML. Caralluma fimbriata supplementation improves the appetite behavior of children and adolescents with Prader-Willi syndrome. N Am J Med Sci 2015;7(11):509-16. View abstract.
  • Kell G, Rao A, Katsikitis M. A randomised placebo controlled clinical trial on the efficacy of Caralluma fimbriata supplement for reducing anxiety and stress in healthy adults over eight weeks. J Affect Disord. 2019;246:619-626. View abstract.
  • Kuriyan R, Raj T, Srinivas SK, et al. Effect of Caralluma Fimbriata extract on appetite, food intake and anthropometry in adult Indian men and women. Appetite 2007;48:338-44. View abstract.
  • Odendaal AY, Deshmukh NS, Marx TK, Schauss AG, Endres JR, Clewell AE. Safety assessment of a hydroethanolic extract of Caralluma fimbriata. Int J Toxicol 2013;32(5):385-94. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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