Krill oil comes from a tiny, shrimp-like marine animal. It's rich in the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

The benefits of krill oil seem to come from its omega-3 fatty acid content. The body doesn't produce many of its own omega-3 fatty acids. Omega-3 fatty acids can reduce pain and swelling and also prevent the blood from clotting easily.

People use krill oil for dry eye. It is also used for high levels of triglycerides in the blood, high cholesterol, diabetes, depression, and many other conditions, but there is no good scientific evidence to support many of these uses.

Don't confused krill oil with algal oil, cod liver oil, fish oil, or shark liver oil. These are not the same.

Uses & Effectiveness ?

Possibly Effective for

  • Dry eye. Taking krill oil by mouth for about 3 months improves dry eye symptoms such as redness.
There is interest in using krill oil for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Krill oil is possibly safe when used for up to 6 months. Side effects might include stomach upset, decreased appetite, heartburn, fishy burps, bloating, diarrhea, and nausea.

Special Precautions and Warnings

Pregnancy and breast-feeding: There isn't enough reliable information to know if krill oil is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Krill oil can slow blood clotting. It might increase the risk of bleeding in people with bleeding disorders.

Seafood allergy: Some people who are allergic to seafood might also be allergic to krill oil supplements. Avoid using krill oil or use it cautiously if you have a seafood allergy.

Surgery: Krill oil can slow blood clotting. It might increase the risk of bleeding during and after surgery. Stop using krill oil at least 2 weeks before a scheduled surgery.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with KRILL OIL

    Krill oil might slow blood clotting. Taking krill oil along with medications that also slow blood clotting might increase the risk of bruising and bleeding.

  • Medications for diabetes (Antidiabetes drugs) interacts with KRILL OIL

    Krill oil might lower blood sugar levels. Taking krill oil along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.


Krill oil has most often been used by adults in doses of 1-4 grams by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
View References

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2018.