Overview

Theaflavin is a chemical in black tea that is formed from fermentation of green tea. It is used as medicine.

People take theaflavin for high levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia), heart disease, obesity, and cancer, but there is no good scientific evidence to support these uses.

How does it work ?

Theaflavin has antioxidant, antiviral, and anti-cancer effects in test tube experiments and in animals. Theaflavin might also normalize blood sugar levels. The effects of theaflavin in humans are not well studied.

Uses & Effectiveness ?

Insufficient Evidence for

  • High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia).Early research shows that taking a green tea extract with extra theaflavin seems to help reduce cholesterol.
  • Heart disease.
  • Cancer.
  • Other conditions.
More evidence is needed to rate the effectiveness of theaflavin for these uses.

Side Effects

When taken by mouth: Theaflavin is LIKELY SAFE in the amounts found in brewed black tea. Theaflavin is POSSIBLY SAFE in the amounts found in medicine when used for up to 12 weeks.

Special Precautions and Warnings

Pregnancy and breast-feeding: There isn't enough reliable information available to know if theaflavin is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Medications for diabetes (Antidiabetes drugs) interacts with THEAFLAVIN

    Theaflavin might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking theaflavin along with diabetes medications might cause your blood sugar to go too low. But more evidence is needed to know if this interaction is a big concern. Monitor your blood sugar closely.

    Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

  • Medications moved by pumps in cells (Organic anion-transporting polypeptide substrates) interacts with THEAFLAVIN

    Some medications are moved by pumps in cells. Theaflavin might change how these pumps work and decrease how much of some medications get absorbed by the body. This could make these medications less effective.

    Some of these medications that are moved by pumps in cells include bosentan (Tracleer), celiprolol (Celicard, others), etoposide (VePesid), fexofenadine (Allegra), fluoroquinolone antibiotics, glyburide (Micronase, Diabeta), irinotecan (Camptosar), methotrexate, nadolol (Corgard), paclitaxel (Taxol), saquinavir (Fortovase, Invirase), rifampin, statins, talinolol, torsemide (Demadex), troglitazone, and valsartan (Diovan).

Dosing

The appropriate dose of theaflavin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for theaflavin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2018.