ECKLONIA CAVA

OTHER NAME(S):

Algae, Algas Pardas, Algues Brunes, Algues Brunes Marines, Brown Alga, Brown Algae, Brown Seaweed, EC, ECE, Ecklonia Extract, Eckol, LAD103, Marine Brown Algae, Phlorotannin, Ventol.

Overview

Overview Information

Ecklonia cava is a type of algae that is used as food and medicine. It grows in parts of Asia.

Ecklonia cava is used for cancer, arthritis, stress, obesity, heart disease, high cholesterol, athletic performance, diabetes, and many other conditions, but there is no good scientific evidence to support these uses.

How does it work?

Ecklonia cava contains several chemicals that work as antioxidants. These chemicals are thought to prevent damage to the body that can lead to cancer and other conditions. Chemicals contained in Ecklonia cava might also have effects on inflammation and the body's immune system.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Athletic performance. Early research shows that adding an extract of Ecklonia cava to a sport drink might help people to exercise longer than just the sports drink alone.
  • Prediabetes. Early research shows that taking Ecklonia cava extract might reduce blood sugar levels after a meal. But it doesn't seem to lower sugar levels between meals or help the body to use sugar more effectively.
  • Obesity. Early research shows that taking an extract of Ecklonia cava helps with weight loss in people that are overweight.
  • Cancer.
  • Fibromyalgia.
  • Arthritis.
  • Chronic fatigue syndrome.
  • Insomnia.
  • High cholesterol.
  • Heart disease.
  • Asthma.
  • Gulf War syndrome.
  • Post-traumatic stress disorder (PTSD).
  • Multiple-chemical sensitivity.
  • Other conditions.
More evidence is needed to rate the effectiveness of Ecklonia cava.

Side Effects

Side Effects & Safety

When taken by mouth: Extracts of Ecklonia cava are POSSIBLY SAFE when used for up to 12 weeks.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if it is safe to use Ecklonia cava when pregnant or breast-feeding. Stay on the safe side and avoid use.

Interactions

Interactions?

We currently have no information for ECKLONIA CAVA Interactions.

Dosing

Dosing

The appropriate dose of Ecklonia cava depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Ecklonia cava. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Artan M, Li Y, Karadeniz F, et al. Anti-HIV-1 activity of phloroglucinol derivative, 6,6'-bieckol, from Ecklonia cava. Bioorg Med Chem 2008;16:7921-6. View abstract.
  • Athukorala Y, Kim KN, Jeon YJ. Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food Chem Toxicol 2006;44:1065-74. View abstract.
  • Jung WK, Ahn YW, Lee SH, et al. Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-kappaB pathways. Food Chem Toxicol 2009;47:410-7. View abstract.
  • Kang K, Hwang HJ, Hong DH, et al. Antioxidant and antiinflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explant culture. Res Commun Mol Pathol Pharmacol 2004;115-116:77-95. View abstract.
  • Kang KA, Lee KH, Chae S, et al. Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells. FEBS Lett 2005;579:6295-304. View abstract.
  • Kang KA, Zhang R, Lee KH, et al. Protective effect of triphlorethol-A from Ecklonia cava against ionizing radiation in vitro. J Radiat Res (Tokyo) 2006;47:61-8. View abstract.
  • Kim MM, Ta QV, Mendis E, et al. Phlorotannins in Ecklonia cava extract inhibit matrix metalloproteinase activity. Life Sci 2006;79:1436-43. View abstract.
  • Kim SK, Lee DY, Jung WK, et al. Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: role of suppressor of cytokine signaling. Biomed Pharmacother 2008;62:289-96. View abstract.
  • Li Y, Qian ZJ, Ryu B, et al. Chemical components and its antioxidant properties in vitro: an edible marine brown alga, Ecklonia cava. Bioorg Med Chem 2009;17:1963-73. View abstract.
  • Park E, Ahn GN, Lee NH, et al. Radioprotective properties of eckol against ionizing radiation in mice. FEBS Lett 2008;582:925-30. View abstract.
  • Shin HC, Hwang HJ, Kang KJ, Lee BH. An antioxidative and antiinflammatory agent for potential treatment of osteoarthritis from Ecklonia cava. Arch Pharm Res 2006;29:165-71. View abstract.
  • Artan M, Li Y, Karadeniz F, et al. Anti-HIV-1 activity of phloroglucinol derivative, 6,6'-bieckol, from Ecklonia cava. Bioorg Med Chem 2008;16:7921-6. View abstract.
  • Athukorala Y, Kim KN, Jeon YJ. Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food Chem Toxicol 2006;44:1065-74. View abstract.
  • Jung WK, Ahn YW, Lee SH, et al. Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-kappaB pathways. Food Chem Toxicol 2009;47:410-7. View abstract.
  • Kang K, Hwang HJ, Hong DH, et al. Antioxidant and antiinflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explant culture. Res Commun Mol Pathol Pharmacol 2004;115-116:77-95. View abstract.
  • Kang KA, Lee KH, Chae S, et al. Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells. FEBS Lett 2005;579:6295-304. View abstract.
  • Kang KA, Zhang R, Lee KH, et al. Protective effect of triphlorethol-A from Ecklonia cava against ionizing radiation in vitro. J Radiat Res (Tokyo) 2006;47:61-8. View abstract.
  • Kim MM, Ta QV, Mendis E, et al. Phlorotannins in Ecklonia cava extract inhibit matrix metalloproteinase activity. Life Sci 2006;79:1436-43. View abstract.
  • Kim SK, Lee DY, Jung WK, et al. Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: role of suppressor of cytokine signaling. Biomed Pharmacother 2008;62:289-96. View abstract.
  • Lee SH, Jeon YJ. Efficacy and safety of a dieckol-rich extract (AG-dieckol) of brown algae, Ecklonia cava, in pre-diabetic individuals: a double-blind, randomized, placebo-controlled clinical trial. Food Funct. 2015;6(3):853-8. View abstract.
  • Li Y, Qian ZJ, Ryu B, et al. Chemical components and its antioxidant properties in vitro: an edible marine brown alga, Ecklonia cava. Bioorg Med Chem 2009;17:1963-73. View abstract.
  • Oh JK, Shin YO, Yoon JH, Kim SH, Shin HC, Hwang HJ. Effect of supplementation with Ecklonia cava polyphenol on endurance performance of college students. Int J Sport Nutr Exerc Metab. 2010;20(1):72-9. View abstract.
  • Park E, Ahn GN, Lee NH, et al. Radioprotective properties of eckol against ionizing radiation in mice. FEBS Lett 2008;582:925-30. View abstract.
  • Shin HC, Hwang HJ, Kang KJ, Lee BH. An antioxidative and antiinflammatory agent for potential treatment of osteoarthritis from Ecklonia cava. Arch Pharm Res 2006;29:165-71. View abstract.
  • Shin HC, Kim SH, Park Y, Lee BH, Hwang HJ. Effects of 12-week oral supplementation of Ecklonia cava polyphenols on anthropometric and blood lipid parameters in overweight Korean individuals: a double-blind randomized clinical trial. Phytother Res. 2012;26(3):363-8. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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