WHITE MULBERRY

OTHER NAME(S):

Chinese White Mulberry, Chi Sang, Chin Sang, Common Mulberry, Egyptian Mulberry, Mon Tea, Mora, Moral Blanco, Morera Blanca, Morin, Morus alba, Morus indica, Morus multicaulis, Mûrier Blanc, Mûrier Blanc de Chine, Mûrier Commun, Mûrier du Ver à Soie, Russian Mulberry, Silkworm Mulberry.<br/><br/>

Overview

Overview Information

White mulberry is an herb. The powdered leaves are most commonly used for medicine. The fruit can be used for food, either raw or cooked.

White mulberry is often tried in order to help treat diabetes. It is also tried for treating high cholesterol levels, high blood pressure, the common cold and its symptoms, muscle and joint pain such as from arthritis, constipation, dizziness, ringing in the ears, hair loss, and premature graying.

White mulberry is native to China and is the food of silkworms. It was introduced into the United States in colonial times, during an attempt to establish a silk industry. The wood is very flexible and durable and has been used to make tennis rackets, hockey sticks, furniture, and boats.

How does it work?

There are some chemicals in white mulberry that work in a similar way to some medicines used for type 2 diabetes. They slow the breakdown of sugars in the gut so that they are absorbed more slowly into the blood. This helps the body keep blood sugar levels in the desirable range.

Uses

Uses & Effectiveness?

Possibly Effective for

Insufficient Evidence for

  • High blood cholesterol. In a small study of people with type 2 diabetes, white mulberry leaf, 1 gram taken 3 times daily for 4 weeks, reduced total cholesterol by 12%, and LDL (“bad”) cholesterol by 23%, and increased HDL (“good”) cholesterol by 18%.
  • Common cold.
  • Cough.
  • Sore throat.
  • Muscle and joint pain.
  • High blood pressure.
  • Asthma.
  • Constipation.
  • Dizziness and ringing in the ears.
  • Hair loss and premature graying.
  • Other conditions.
More evidence is needed to rate the effectiveness of white mulberry for these uses.

Side Effects

Side Effects & Safety

White mulberry is POSSIBLY SAFE for most people when the powdered leaf is taken by mouth for up to 5 weeks. Side effects have not been reported in studies; however, not very many studies have been done.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of white mulberry during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Diabetes: White mulberry might lower blood sugar levels in people with diabetes. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use white mulberry.

Interactions

Interactions?

We currently have no information for WHITE MULBERRY Interactions.

Dosing

Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For diabetes: 1 gram of the powdered leaf taken three times daily.
  • For high cholesterol levels: 1 gram of the powdered leaf taken three times daily.

View References

REFERENCES:

  • Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. View abstract.
  • Andallu B, Varadacharyulu NC. Antioxidant role of mulberry (Morus indica L. cv. Anantha) leaves in streptozotocin-diabetic rats. Clin Chim Acta 2003;338:3-10. View abstract.
  • Andallu B, Varadacharyulu NC. Gluconeogenic substrates and hepatic gluconeogenic enzymes in streptozotocin-diabetic rats: effect of mulberry (Morus indica L.) leaves. J Med Food 2007;10:41-8. View abstract.
  • Asano N, Oseki K, Tomioka E, et al. N-containing sugars from Morus alba and their glycosidase inhibitory activities. Carbohydr Res 1994;259:243-55. View abstract.
  • Asano N, Yamashita T, Yasuda K, et al. Polyhydroxylated alkaloids isolated from mulberry trees (Morus alba L.) and silkworms (Bombyx mori L.). J Agric Food Chem 2001;49:4208-13. View abstract.
  • Chen J, Li X. Hypolipidemic effect of flavonoids from mulberry leaves in triton WR-1339 induced hyperlipidemic mice. Asia Pac J Clin Nutr 2007;16(Suppl 1):290-4. View abstract.
  • Doi K, Kojima T, Makino M, et al. Studies on the constituents of the leaves of Morus alba L. Chem Pharm Bull 2001;49:151-3. View abstract.
  • Du J, He ZD, Jiang RW, et al. Antiviral flavonoids from the root bark of Morus alba L. Phytochemistry 2003;62:1235-8. View abstract.
  • El-Beshbishy HA, Singab AN, Sinkkonen J, Pihlaja K. Hypolipidemic and antioxidant effects of Morus alba L. (Egyptian mulberry) root bark fractions supplementation in cholesterol-fed rats. Life Sci 2006;78:2724-33. View abstract.
  • Enkhmaa B, Shiwaku K, Katsube T, et al. Mulberry (Morus alba L) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate atherosclerotic lesion development in LDL receptor-deficient mice. J Nutr 2005;135:729-34. View abstract.
  • Hansawasdi C, Kawabata J. Alpha-glucosidase inhibitory effect of mulberry (Morus alba) leaves on Caco-2. Fitoterapia 2006;77:568-73. View abstract.
  • Hwang KH, Kim YK. Promoting effect and recovery activity from physical stress of the fruit of Morus alba. Biofactors 2004;21:267-71. View abstract.
  • Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. View abstract.
  • Lee J, Chae K, Ha J, et al. Regulation of obesity and lipid disorders by herbal extracts from Morus alba, Melissa officinalis, and Artemisia capillaris in high-fat diet-induced obese mice. J Ethnopharmacol 2008;115:263-70. View abstract.
  • Lee SH, Choi SY, Kim H, et al. Mulberroside F isolated from the leaves of Morus alba inhibits melanin biosynthesis. Biol Pharm Bull 2002;25:1045-8. View abstract.
  • Moore LM. Plant Guide: White Mulberry. United States Department of Agriculture, Natural Resources Conservation Service. Available at: http://plants.usda.gov/plantguide/pdf/pg_moal.pdf. (Accessed 3 September 2009).
  • Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. View abstract.
  • Oku T, Yamada M, Nakamura M, et al. Inhibitory effects of extractives from leaves of Morus alba on human and rat small intestinal disaccharidase activity. Br J Nutr 2006;95:933-8. View abstract.
  • Park KM, You JS, Lee HY, et al. Kuwanon G: an antibacterial agent from the root bark of Morus alba against oral pathogens. J Ethnopharmacol 2003;84:181-5. View abstract.
  • Skupien K, Kostrzewa-Nowak D, Oszmianski J, Tarasiuk J. In vitro antileukaemic activity of extracts from chokeberry (Aronia melanocarpa [Michx] Elliott) and mulberry (Morus alba L.) leaves against sensitive and multidrug resistant HL60 cells. Phytother Res 2008;22:689-94. View abstract.
  • Yu Z, Fong WP, Cheng CH. The dual actions of morin (3,5,7,2',4'-pentahydroxyflavone) as a hypouricemic agent: uricosuric effect and xanthine oxidase inhibitory activity. J Pharmacol Exp Ther 2006;316:169-75. View abstract.
  • Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. View abstract.
  • Andallu B, Varadacharyulu NC. Antioxidant role of mulberry (Morus indica L. cv. Anantha) leaves in streptozotocin-diabetic rats. Clin Chim Acta 2003;338:3-10. View abstract.
  • Andallu B, Varadacharyulu NC. Gluconeogenic substrates and hepatic gluconeogenic enzymes in streptozotocin-diabetic rats: effect of mulberry (Morus indica L.) leaves. J Med Food 2007;10:41-8. View abstract.
  • Asano N, Oseki K, Tomioka E, et al. N-containing sugars from Morus alba and their glycosidase inhibitory activities. Carbohydr Res 1994;259:243-55. View abstract.
  • Asano N, Yamashita T, Yasuda K, et al. Polyhydroxylated alkaloids isolated from mulberry trees (Morus alba L.) and silkworms (Bombyx mori L.). J Agric Food Chem 2001;49:4208-13. View abstract.
  • Chen J, Li X. Hypolipidemic effect of flavonoids from mulberry leaves in triton WR-1339 induced hyperlipidemic mice. Asia Pac J Clin Nutr 2007;16(Suppl 1):290-4. View abstract.
  • Doi K, Kojima T, Makino M, et al. Studies on the constituents of the leaves of Morus alba L. Chem Pharm Bull 2001;49:151-3. View abstract.
  • Du J, He ZD, Jiang RW, et al. Antiviral flavonoids from the root bark of Morus alba L. Phytochemistry 2003;62:1235-8. View abstract.
  • El-Beshbishy HA, Singab AN, Sinkkonen J, Pihlaja K. Hypolipidemic and antioxidant effects of Morus alba L. (Egyptian mulberry) root bark fractions supplementation in cholesterol-fed rats. Life Sci 2006;78:2724-33. View abstract.
  • Enkhmaa B, Shiwaku K, Katsube T, et al. Mulberry (Morus alba L) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate atherosclerotic lesion development in LDL receptor-deficient mice. J Nutr 2005;135:729-34. View abstract.
  • Hansawasdi C, Kawabata J. Alpha-glucosidase inhibitory effect of mulberry (Morus alba) leaves on Caco-2. Fitoterapia 2006;77:568-73. View abstract.
  • Hwang KH, Kim YK. Promoting effect and recovery activity from physical stress of the fruit of Morus alba. Biofactors 2004;21:267-71. View abstract.
  • Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. View abstract.
  • Lee J, Chae K, Ha J, et al. Regulation of obesity and lipid disorders by herbal extracts from Morus alba, Melissa officinalis, and Artemisia capillaris in high-fat diet-induced obese mice. J Ethnopharmacol 2008;115:263-70. View abstract.
  • Lee SH, Choi SY, Kim H, et al. Mulberroside F isolated from the leaves of Morus alba inhibits melanin biosynthesis. Biol Pharm Bull 2002;25:1045-8. View abstract.
  • Moore LM. Plant Guide: White Mulberry. United States Department of Agriculture, Natural Resources Conservation Service. Available at: http://plants.usda.gov/plantguide/pdf/pg_moal.pdf. (Accessed 3 September 2009).
  • Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. View abstract.
  • Oku T, Yamada M, Nakamura M, et al. Inhibitory effects of extractives from leaves of Morus alba on human and rat small intestinal disaccharidase activity. Br J Nutr 2006;95:933-8. View abstract.
  • Park KM, You JS, Lee HY, et al. Kuwanon G: an antibacterial agent from the root bark of Morus alba against oral pathogens. J Ethnopharmacol 2003;84:181-5. View abstract.
  • Skupien K, Kostrzewa-Nowak D, Oszmianski J, Tarasiuk J. In vitro antileukaemic activity of extracts from chokeberry (Aronia melanocarpa [Michx] Elliott) and mulberry (Morus alba L.) leaves against sensitive and multidrug resistant HL60 cells. Phytother Res 2008;22:689-94. View abstract.
  • Yu Z, Fong WP, Cheng CH. The dual actions of morin (3,5,7,2',4'-pentahydroxyflavone) as a hypouricemic agent: uricosuric effect and xanthine oxidase inhibitory activity. J Pharmacol Exp Ther 2006;316:169-75. View abstract.

More Resources for WHITE MULBERRY

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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