DENDROBIUM

OTHER NAME(S):

Dendrobe Noble, Dendrobium Extract, Dendrobium nobile, Dendrobium officinale, Extrait de Dendrobium, Jin Chai Shi Hu (D. nobile), Nobile Dendrobium (D. nobile), Orchid Stem, Stem-Orchid, Tie Pi Shi (D. officinale), Vinterdendrobium (D. nobile).<br/><br/>

Overview

Overview Information

Dendrobium is in the orchid plant family. This type of orchid is native to China, Hong Kong, Taiwan, India, Thailand, Vietnam, and other temperate and tropical Asian regions.

Traditionally, dendrobium plants have been used in Traditional Chinese medicine. Today, dendrobium is showing up in pre-workout supplements used to boost physical and athletic performance. Some experts are claiming that dendrobium will be the next hot stimulant supplement. Some are touting it as a replacement for the stimulant dimethylamylamine (DMAA).

As of March 16, 2012, the manufacturer of a popular dendrobium supplement (Craze, Driven Sports) was the subject of a class action lawsuit. The lawsuit alleges that the product contains amphetamine drugs, that the product is manufactured in a non-compliant facility, and that the ingredient, dendrobium, is a new dietary ingredient (NDI), which requires an NDI notification to FDA. There is concern that this and other dendrobium containing products might be spiked with synthetic stimulant drugs. For example, the dendrobium-containing commercial product Craze by Driven Sports contains the stimulant phenylethylamine which some experts say does not occur naturally in dendrobium plants. Phenylethylamine is a stimulant with effects similar to amphetamine.

How does it work?

Dendrobium contains several chemicals. Some of these chemicals might have effects in the body. They might lower blood pressure, increase blood sugar, and reduce pain. They might also increase the chance of seizure. However, none of these effects have been studied in people. Therefore, the effects of dendrobium in people are not clear.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Athletic performance.
  • Physical performance.
  • Dry mouth.
  • Cough.
  • Fever.
  • Heat stroke.
  • Thirst.
  • Boosting immune function.
  • Vomiting.
  • Abdominal pain.
  • Impotence.
  • Anorexia.
  • Tuberculosis.
  • Other conditions.
More evidence is needed to rate the effectiveness of dendrobium for these uses.

Side Effects

Side Effects & Safety

There isn't enough information to know if dendrobium is safe or what side effects it might cause.

Special Precautions & Warnings:

Pregnancy and Breastfeeding: There isn't enough information to know if dendrobium is safe to take during pregnancy or breastfeeding. Until more is known, avoid using.

Seizures: There is a concern that dendrobium could potentially increase the chance of seizure in some people. Dendrobium contains a chemical that might increase the chance of seizure. If you have ever had a seizure, don’t use dendrobium.

Interactions

Interactions?

We currently have no information for DENDROBIUM Interactions.

Dosing

Dosing

The appropriate dose of dendrobium depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for dendrobium. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Danniells S. Dendrobium-containing Craze pre-workout supplement hit with CA class action. Nutraingredients-USA.com, May 21, 2012. Available at: http://www.nutraingredients-usa.com/Regulation/Dendrobium-containing-Craze-pre-workout-supplement-hit-with-CA-class-action (Accessed May 23, 2012).
  • Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  • Parker EM, Cubeddu LX. Comparative effects of amphetamine, phenylethylamine and related drugs on dopamine efflux, dopamine uptake and mazindol binding. J Pharm Exp Therapeutics 1988;245:199-210. View abstract.
  • Schultz H. Is DMAA successor dendrobium legit? Questions about the chemistry of dendrobium extract. Functional Ingredients eNewsletter, May 17, 2012. Available at: http://newhope360.com/regulation-and-legislation/dmaa-successor-dendrobium-legit?page=2 (Accessed May 23, 2012).
  • Yang HY, Neff NH. Beta-phenylethylamine: a specific substrate for type B monoamine oxidase of brain. J Pharm Exp Therapeutics 1973;187:365-71. View abstract.
  • Danniells S. Dendrobium-containing Craze pre-workout supplement hit with CA class action. Nutraingredients-USA.com, May 21, 2012. Available at: http://www.nutraingredients-usa.com/Regulation/Dendrobium-containing-Craze-pre-workout-supplement-hit-with-CA-class-action (Accessed May 23, 2012).
  • Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  • Parker EM, Cubeddu LX. Comparative effects of amphetamine, phenylethylamine and related drugs on dopamine efflux, dopamine uptake and mazindol binding. J Pharm Exp Therapeutics 1988;245:199-210. View abstract.
  • Schultz H. Is DMAA successor dendrobium legit? Questions about the chemistry of dendrobium extract. Functional Ingredients eNewsletter, May 17, 2012. Available at: http://newhope360.com/regulation-and-legislation/dmaa-successor-dendrobium-legit?page=2 (Accessed May 23, 2012).
  • Yang HY, Neff NH. Beta-phenylethylamine: a specific substrate for type B monoamine oxidase of brain. J Pharm Exp Therapeutics 1973;187:365-71. View abstract.

More Resources for DENDROBIUM

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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