CHUCHUHUASI

OTHER NAME(S):

Chuchasha, Chuchuasi, Chuchuhuasca, Chuchuhuasha, Maytenus krukovii, Maytenus laevis, Maytenus macrocarpa.

Overview

Overview Information

Chuchuhuasi is a tree. The barks, roots, and leaves are used to make medicine.

People take chuchuhuasi by mouth for arthritis, back pain, broken bones, diarrhea, complications after childbirth, joint disorders, sexual arousal, and as a tonic.

People apply chuchuhuasi to the skin for skin cancer.

As a food, chuchuhuasi is used as a flavoring agent.

How does it work?

Chuchuhuasi might slow cancer growth. It might also prevent bacterial and fungal infections. Chuchuhuasi contains chemicals that have antioxidant effects.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Arthritis.
  • Back pain.
  • Broken bones.
  • Diarrhea.
  • Complications after childbirth.
  • Joint disorders.
  • Sexual arousal.
  • Other conditions.
More evidence is needed to rate the effectiveness of chuchuhuasi for these uses.

Side Effects

Side Effects & Safety

It isn’t known if chuchuhuasi is safe or what the possible side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of chuchuhuasi during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Interactions

Interactions?

We currently have no information for CHUCHUHUASI Interactions.

Dosing

Dosing

The appropriate dose of chuchuhuasi depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for chuchuhuasi. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Chavez H, Callo N, Estevez-Braun A, et al. Sesquiterpene polyol esters from the leaves of maytenus macrocarpa. J Nat Prod 1999;62(11):1576-7. View abstract.
  • Chavez H, Estevez-Braun A, Ravelo AG, Gonzalez AG. Friedelane triterpenoids from Maytenus macrocarpa. J Nat Prod 1998;61(1):82-5. View abstract.
  • Chavez H, Rodriguez G, Estevez-Braun A, et al. Macrocarpins A-D, new cytotoxic nor-triterpenes from Maytenus macrocarpa. Bioorg Med Chem Lett 2000;10(8):759-62. View abstract.
  • Melo AM, Jardim ML, De Santana CF, et al. First observations on the topical use of Primin, Plumbagin and Maytenin in patients with skin cancer. Rev Inst Antibiot (Recife) 1974;14(1-2):9-16. View abstract.
  • Nakagawa H, Takaishi Y, Fujimoto Y, et al. Chemical constituents from the Colombian medicinal plant Maytenus laevis. J Nat Prod 2004;67(11):1919-24. View abstract.
  • Perez-Victoria JM, Tincusi BM, Jimenez IA, et al. New natural sesquiterpenes as modulators of daunomycin resistance in a multidrug-resistant Leishmania tropica line. J Med Chem 1999;42(21):4388-93. View abstract.
  • Sekar KV, Sneden AT, Flores FA. Mayteine and 6-benzoyl-6-deacetylmayteine from Maytenus krukovii. Planta Med 1995;61(4):390. View abstract.
  • Shirota O, Sekita S, Satake M, et al. Nine new isoxuxuarine-type triterpene dimers from Maytenus chuchuhuasca. Chem Biodivers 2004;1(9):1296-1307. View abstract.
  • Shirota O, Sekita S, Satake M, et al. Nine regioisomeric and stereoisomeric triterpene dimers from Maytenus chuchuhuasca. Chem Pharm Bull (Tokyo) 2004;52(6):739-46. View abstract.
  • Shirota O, Sekita S, Satake M, et al. Two cangorosin A type triterpene dimers from Maytenus chuchuhuasca. Chem Pharm Bull (Tokyo) 2004;52(9):1148-50. View abstract.
  • Torpocco V, Chavez H, Estevez-Braun A, Ravelo AG. New dammarane triterpenes from Maytenus macrocarpa. Chem Pharm Bull (Tokyo) 2007;55(5):812-4. View abstract.
  • Bruni R, Rossi D, Muzzoli M, et al. Antimutagenic, antioxidant and antimicrobial properties of Maytenus krukovii bark. Fitoterapia 2006;77(7-8):538-45. View abstract.
  • Chavez H, Callo N, Estevez-Braun A, et al. Sesquiterpene polyol esters from the leaves of maytenus macrocarpa. J Nat Prod 1999;62(11):1576-7. View abstract.
  • Chavez H, Estevez-Braun A, Ravelo AG, Gonzalez AG. Friedelane triterpenoids from Maytenus macrocarpa. J Nat Prod 1998;61(1):82-5. View abstract.
  • Chavez H, Rodriguez G, Estevez-Braun A, et al. Macrocarpins A-D, new cytotoxic nor-triterpenes from Maytenus macrocarpa. Bioorg Med Chem Lett 2000;10(8):759-62. View abstract.
  • Dicarlo FJ, Haynes LJ, Silver NJ, Phillips GE. Protection of mice against gram-positive bacteria with Maytenus laevis and other res stimulants. Proc Soc Exp Biol Med 1964;116:195-7. View abstract.
  • Gonzalez JG, delle Monache G, delle Monache F, Marini-Bettolo GB. Chuchuhuasha - a drug used in folk medicine in the Amazonian and Andean areas. A chemical study of Maytenus laevis. J Ethnopharmacol 1982;5(1):73-7. View abstract.
  • Kloucek P, Polesny Z, Svobodova B, et al. Antibacterial screening of some Peruvian medicinal plants used in Callería District. J Ethnopharmacol 2005;99(2):309-12. View abstract.
  • Kloucek P, Svobodova B, Polesny Z, et al. Antimicrobial activity of some medicinal barks used in Peruvian Amazon. J Ethnopharmacol 2007;111(2):427-9. View abstract.
  • Melo AM, Jardim ML, De Santana CF, et al. First observations on the topical use of Primin, Plumbagin and Maytenin in patients with skin cancer. Rev Inst Antibiot (Recife) 1974;14(1-2):9-16. View abstract.
  • Morita H, Hirasawa Y, Muto A, et al. Antimitotic quinoid triterpenes from Maytenus chuchuhuasca. Bioorg Med Chem Lett 2008;18(3):1050-2. View abstract.
  • Nakagawa H, Takaishi Y, Fujimoto Y, et al. Chemical constituents from the Colombian medicinal plant Maytenus laevis. J Nat Prod 2004;67(11):1919-24. View abstract.
  • Patel D, Kaur G, Sawant MG, Deshmukh P. Herbal Medicine - A natural cure to arthritis. Indian J Nat Prod Resources 2013;4(1):27-33.
  • Perez-Victoria JM, Tincusi BM, Jimenez IA, et al. New natural sesquiterpenes as modulators of daunomycin resistance in a multidrug-resistant Leishmania tropica line. J Med Chem 1999;42(21):4388-93. View abstract.
  • Piacente S, Tommasi ND, Pizza C. Laevisines A and B: two new sesquiterpene-pyridine alkaloids from maytenus laevis. J Nat Prod 1999;62(1):161-3. View abstract.
  • Salazar A, Loja B, Rabanal A, et al. Comparación de los usos del chuchuhuasi (Maytenus macrocarpa) entre indígenas Bora-Bora de Loreto y chamanes de Lima (Perú). Revista de Fitoterapia 2013;13(1):61-69.
  • Sekar KV, Sneden AT, Flores FA. Mayteine and 6-benzoyl-6-deacetylmayteine from Maytenus krukovii. Planta Med 1995;61(4):390. View abstract.
  • Shirota O, Sekita S, Satake M, et al. Nine new isoxuxuarine-type triterpene dimers from Maytenus chuchuhuasca. Chem Biodivers 2004;1(9):1296-1307. View abstract.
  • Shirota O, Sekita S, Satake M, et al. Nine regioisomeric and stereoisomeric triterpene dimers from Maytenus chuchuhuasca. Chem Pharm Bull (Tokyo) 2004;52(6):739-46. View abstract.
  • Shirota O, Sekita S, Satake M, et al. Two cangorosin A type triterpene dimers from Maytenus chuchuhuasca. Chem Pharm Bull (Tokyo) 2004;52(9):1148-50. View abstract.
  • Simons A. The Healing Power of Plants. Medicinal Plants from Abuta and Acerola to Yohimbe and Yucca: a Practical Selection. Coburg, Germany: MayaMedia Publishing, 2013.
  • Torpocco V, Chavez H, Estevez-Braun A, Ravelo AG. New dammarane triterpenes from Maytenus macrocarpa. Chem Pharm Bull (Tokyo) 2007;55(5):812-4. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.