BRIDELIA: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Bridelia is the name for a group of plants in the same family. The leaf, stem bark, and root of some of these plants are used to make medicine.

Bridelia leaf, stem bark, or root is used for many conditions, but there is no good scientific evidence to support its use.

How does it work ?

Bridelia might reduce swelling, lessen pain, and lower fevers. Bridelia might also prevent the growth of organisms that cause infections.

Uses & Effectiveness ?

Insufficient Evidence for

To prevent pregnancy.
To cause labor.
Malaria.
HIV/AIDS.
Anemia.
Asthma.
Cancer.
Colic.
Cough.
Diabetes.
Diarrhea.
Enlarged spleen.
Gonorrhea.
Headache.
Hernia.
Joint pain.
Menstrual cramps (dysmenorrhea).
Wound healing.
Stomach aches and other stomach problems.
Syphilis.
Thrush.
To kill parasites.
Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs).
Yellow fever.
Yellow skin discoloration (jaundice).
Other conditions.

More evidence is needed to rate the effectiveness of Bridelia for these uses.

Side Effects

Special Precautions and Warnings

When taken by mouth: There isn't enough reliable information to know if Bridelia is safe or what the side effects might be.

When applied to the skin: There isn't enough reliable information to know if Bridelia is safe or what the side effects might be. Pregnancy and breast-feeding: Bridelia is LIKELY UNSAFE when used during pregnancy. There is concern that Bridelia might stimulate the uterus and cause labor. Avoid using.

There isn't enough reliable information to know if Bridelia is safe to use when breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Bridelia might slow blood clotting. This might increase the risk of bleeding or bruising in people with bleeding disorders.

Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Bridelia might have the same effects as the female hormone estrogen. If you have any condition that might be made worse by exposure to estrogen, don't use Bridelia.

Low blood pressure: Bridelia might decrease blood pressure. Don't take Bridelia if you already have low blood pressure.

Surgery: Bridelia might slow blood clotting. In theory, Bridelia might cause extra bleeding or affect blood pressure control during and after surgery. Stop using it at least 2 weeks before a scheduled surgery.

Interactions ?

Moderate Interaction

Be cautious with this combination

Estrogens interacts with BRIDELIA
Bridelia might have some of the same effects as estrogen. However, Bridelia is not as strong as estrogen pills. Taking Bridelia along with estrogen pills might decrease the effects of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Medications for high blood pressure (Antihypertensive drugs) interacts with BRIDELIA
Bridelia might lower blood pressure. Taking Bridelia along with medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with BRIDELIA
Bridelia might slow blood clotting. Taking Bridelia along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Dosing

The appropriate dose of Bridelia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Bridelia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

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Talla E, Djamen D, Djoulde D, et al. Antimicrobial activity of Bridelia ferruginea leaves extracts. Fitoterapia 2002;73(4):343-5. View abstract.

Theophile D, Laure NE, Benoit NT, et al. Antinociceptive and anti-inflammatory effects of the ethyl acetate stem bark extract of Bridelia scleroneura (Euphorbiaceae). Inflammopharmacology 2006;14(1-2):42-7. View abstract.

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