19-N-Andro, 19-nor-4-androstene-3,17-dione, 19-nor-A-dione, 19-Norandrostenedione, 19nor-dehydroepiandrosterone, 19-nor-dehydroepiandrosterone, 19nor-DHEA, 19-Nordéhydroépiandrostérone, 19-Norandrost-4-ene-3,17-dione, Estr-4-ene-3,17-dione.


Overview Information

19-nor-DHEA is a type of chemical known as a "prohormone." These chemicals are changed by the body to other "muscle-building" hormones such as testosterone. Very little is known about the safety of 19-nor-DHEA. There is concern it might cause serious side effects similar to those caused by other "muscle-building" hormones.

19-nor-DHEA is included as an ingredient in a variety of supplements marketed to athletes and bodybuilders.

How does it work?

After 19-nor-DHEA is taken, the body is thought to change it into other chemicals called hormones. Some of these hormones include chemicals that are similar to testosterone. Testosterone and similar hormones can help build muscle, but can also cause dangerous side effects.


Uses & Effectiveness?

Insufficient Evidence for

  • Athletic performance.
  • Other conditions.
More evidence is needed to rate 19-nor-DHEA for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: 19-nor-DHEA is POSSIBLY UNSAFE. 19-nor-DHEA is changed by the body to other "muscle building" hormones such as testosterone. There is concern 19-nor-DHEA might cause serious side effects similar to those caused by other "muscle-building" hormones. These serious side effects might include liver damage, kidney damage, and also stroke.

Special Precautions and Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking 19-nor-DHEA if you are pregnant or breast feeding. Stay on the safe side and avoid use.

Heart disease: 19-nor-DHEA might worsen heart disease in some patients.

Liver problems: 19-nor-DHEA might worsen liver problems in some patients.


We currently have no information for 19-NOR-DHEA Interactions.



The appropriate dose of 19-nor-DHEA depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for 19-nor-DHEA. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • 19nor-Dehydroepiandrosterone. ProhormoneDB.com. Available at: https://prohormonedb.com/view-ingredients.asp?n=19nor-Dehydroepiandrosterone&i=319. Accessed: February 29, 2016.
  • Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9. View abstract.
  • Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
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