Ascophyllum nodosum is taken by mouth for dental health, weight loss, or as a source of the mineral iodine. Don't confuse Ascophyllum nodosum with other kinds of seaweed like Bladderwort, Blue-green Algae, Brown Algae, Fucus vesiculosus, or Laminaria, or with the chemical Algin that comes from seaweed.
How does it work ?
Uses & Effectiveness ?
Insufficient Evidence for
- Tooth plaque. Early research shows that taking Ascophyllum nodosum (ProDen PlaqueOff) might help to reduce the build-up of plaque on the teeth.
- A mild form of gum disease (gingivitis). Early research shows that taking Ascophyllum nodosum (ProDen PlaqueOff) does not prevent gingivitis.
- Iodine deficiency. Ascophyllum nodosum contains iodine. Early research shows that taking Ascophyllum nodosum can increase iodine levels in women who have low levels of iodine in the body.
- Stomach or intestinal problems.
- Other conditions.
Special Precautions and Warnings
We currently have no information for ASCOPHYLLUM NODOSUM overview.
Hall, A. C., Fairclough, A. C., Mahadevan, K., and Paxman, J. R. Ascophyllum nodosum enriched bread reduces subsequent energy intake with no effect on post-prandial glucose and cholesterol in healthy, overweight males. A pilot study. Appetite 2012;58(1):379-386. View abstract.
Le Tutour B, Benslimane F, Gouleau MP, and et al. Antioxidant and pro-oxidant activities of the brown algae, Laminaria digitata, Himanthalia elongata, Fucus vesiculosus, Fucus serratus and Ascophyllum nodosum. J Applied Phycology 1998;10(2):121-129.
Paradis, M. E., Couture, P., and Lamarche, B. A randomised crossover placebo-controlled trial investigating the effect of brown seaweed (Ascophyllum nodosum and Fucus vesiculosus) on postchallenge plasma glucose and insulin levels in men and women. Appl.Physiol Nutr.Metab 2011;36(6):913-919. View abstract.
Bahar B, O'Doherty JV, Hayes M, Sweeney T. Extracts of brown seaweeds can attenuate the bacterial lipopolysaccharide-induced pro-inflammatory response in the porcine colon ex vivo. J Anim Sci 2012;90 Suppl 4:46-8. View abstract.
Baldrick FR, McFadden K, Ibars M, et al. Impact of a (poly)phenol-rich extract from the brown algae Ascophyllum nodosum on DNA damage and antioxidant activity in an overweight or obese population: a randomized controlled trial. Am J Clin Nutr. 2018;108(4):688-700. View abstract.
Combet E, Ma ZF, Cousins F, et al. Low-level seaweed supplementation improves iodine status in iodine-insufficient women. Br J Nutr 2014;112:753-61. View abstract.
Corona G, Ji Y, Anegboonlap P, et al. Gastrointestinal modifications and bioavailability of brown seaweed phlorotannins and effects on inflammatory markers. Br J Nutr 2016;115(7):1240-53. View abstract.
Gabbia D, Dall'Acqua S, Di Gangi IM, et al. The phytocomplex from Fucus vesiculosus and Ascophyllum nodosum controls postprandial plasma glucose levels: An in vitro and in vivo study in a mouse model of NASH. Mar Drugs 2017;15(2). pii: E41. View abstract.
Jiang Z, Abu R, Isaka S, et al. Inhibitory effect of orally-administered sulfated polysaccharide ascophyllan isolated from ascophyllum nodosum on the growth of sarcoma-180 solid tumor in mice. Anticancer Res 2014;34(4):1663-71. View abstract.
Marinval N, Saboural P, Haddad O, et al. Identification of a pro-angiogenic potential and cellular uptake mechanism of a LMW highly sulfated fraction of fucoidan from Ascophyllum nodosum. Mar Drugs 2016;14(10). pii: E185. View abstract.
Mayer MA, Finlayson G, Fischman D, et al. Evaluation of the satiating properties of a nutraceutical product containing Garcinia cambogia and Ascophyllum nodosum extracts in healthy volunteers. Food Funct 2014;5:773-9. View abstract.
O'Neill A, Gupta BS, Phillips DH. Distribution of arsenic and risk assessment of activities on a golf course fertilised with arsenic-containing Ascophyllum nodosum seaweed. Sci Total Environ 2014;482-483:252-9. View abstract.
Seeley RH, Schlesinger WH. Sustainable seaweed cutting? The rockweed (Ascophyllum nodosum) industry of Maine and the Maritime Provinces. Ann N Y Acad Sci 2012;1249:84-103. View abstract.
Simmons-Boyce JL, Purcell SL, Nelson CM, MacKinnon SL. Dietary Ascophyllum nodosum increases urinary excretion of tricarboxylic acid cycle intermediates in male Sprague-dawley rats. J Nutr 2009;139:1487-94. View abstract.
Sorge US, Henriksen M, Bastan A, et al. Short communication: Iodine concentrations in serum, milk, and tears after feeding Ascophyllum nodosum to dairy cows-A pilot study. J Dairy Sci 2016;99:8472-6. View abstract.
Steevensz AJ, Mackinnon SL, Hankinson R, et al. Profiling phlorotannins in brown macroalgae by liquid chromatography-high resolution mass spectrometry. Phytochem Anal 2012;23(5):547-53. View abstract.
Terpend K, Bisson JF, Le Gall C, Linares E. Effects of ID-alG on weight management and body fat mass in high-fat-fed rats. Phytother Res 2012;26(5):727-33. View abstract.
van Dijken JW, Koistinen S, Ramberg P. A randomized controlled clinical study of the effect of daily intake of Ascophyllum nodosum alga on calculus, plaque, and gingivitis. Clin Oral Investig 2015;19:1507-18. View abstract.
van Ginneken VJ, Helsper JP, de Visser W, et al. Polyunsaturated fatty acids in various macroalgal species from North Atlantic and tropical seas. Lipids Health Dis 2011;10:104. View abstract.
Zhang W, Du JY, Jiang Z, et al. Ascophyllan purified from Ascophyllum nodosum induces Th1 and Tc1 immune responses by promoting dendritic cell maturation. Mar Drugs 2014;12(7):4148-64. View abstract.