Hydrazine sulfate is used for many types of cancer. It is also used for involuntary weight loss in people with cancer (cachexia or wasting syndrome), but there is no good scientific evidence to support these uses. Using hydrazine sulfate may also be unsafe.
How does it work ?
Uses & Effectiveness ?
Possibly Ineffective for
- Colon and rectal cancer. Taking hydrazine sulfate by mouth does not improve the health of people who have colorectal cancer that has spread throughout the body (metastasized).
- Cancer. Research shows that hydrazine sulfate is ineffective for treating ovarian cancer, colorectal cancer, breast cancer, lung cancer, pancreatic cancer, cervical cancer, prostate cancer, uterine cancer, melanoma, and other kinds of cancer.
Likely InEffective for
Insufficient Evidence for
- Brain tumor. Taking hydrazine sulfate along with chemotherapy may improve nerve-related symptoms in people with brain cancer. It may also help reduce the size of tumors in people with a specific type of brain cancer called glioblastoma.
- Involuntary weight loss in people who are very ill (cachexia or wasting syndrome). Early research shows that hydrazine sulfate might slow weight loss in some cancer patients.
- Cancer that starts in white blood cells (Hodgkin lymphoma). Early research shows that hydrazine sulfate might slow the progress of advanced Hodgkin lymphoma.
- Nerve cancer (neuroblastoma). Early research shows that hydrazine sulfate might prevent the growth of neuroblastoma.
- Other conditions.
Special Precautions and Warnings
Diabetes: Hydrazine sulfate might lower blood sugar levels in people with diabetes. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use hydrazine sulfate.
Liver disease: Hydrazine sulfate might damage the liver. It might be unsafe for people with liver disease.
Surgery: Since hydrazine sulfate might affect blood glucose levels, there is a concern that it might interfere with blood glucose control during and after surgery. Stop using hydrazine sulfate at least 2 weeks before a scheduled surgery.
Medications for depression (MAOIs) interacts with HYDRAZINE SULFATE
Hydrazine sulfate contains a chemical that affects the body. This chemical might increase the side effects of some medications used for depression.
Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.
Sedative medications (CNS depressants) interacts with HYDRAZINE SULFATE
Hydrazine sulfate might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking hydrazine sulfate along with sedative medications might cause too much sleepiness.
Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.
Do not take this combination
Medications for diabetes (Antidiabetes drugs) interacts with HYDRAZINE SULFATE
Hydrazine sulfate might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking hydrazine sulfate along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Isoniazid (INH, Nydrazid) interacts with HYDRAZINE SULFATE
Isoniazid is a drug used for tuberculosis. The body breaks isoniazid down to hydrazine. Using both isoniazid and hydrazine might increase the risk of liver damage.
Be cautious with this combination
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