MAGNOLIA

OTHER NAME(S):

Beaver Tree, Bourgeon Floral de Magnolia, Buergeria salicifolia, Chuan houpu, Cortex Magnoliae Officinalis, Flos Magnoliae, Ho-No-Ki, Holly Bay, Hou Po, Hou Po Hua, Houpohua, Houpo, Houpu, Indian Bark, Japanese whitebark, Koboku, Magnolia, Magnolia Bark, Magnolia biondii, Magnolia conspicua, Magnolia denudata, Magnolia emargenata, Magnolia fargesii, Magnolia Flower Bud, Magnolia glauca, Magnolia heptaperta, Magnolia hypoleuca, Magnolia nicholsoniana, Magnolia obovate, Magnolia officinalis, Magnolia proctoriana, Magnolia Rouge, Magnolia salicifolia, Magnolia sargentiana, Magnolia sprengeri, Magnolia taliensis, Magnolia virginiana, Magnolia wilsonii, Magnolia yulan, Red Bay, Red Magnolia, Swamp Laurel, Swamp Sassafras, Sweet Bay, Tuhoupu, White Bay, White Laurel, Xin Ye Hua, Xin Yi Hua, Xinyi, Xinyihua.<br/><br/>

Overview

Overview Information

Magnolia is a plant. People use the bark and flower buds to make medicine.

People use magnolia for conditions including weight loss, stress, gingivitis, plaque, and other conditions, but there is no good scientific evidence to support most of these uses.

How does it work?

Magnolia seems to have anxiety-reducing activity. It might also increase steroid production by the body to treat asthma. Chemicals in magnolia might kill bacteria in the mouth. This might help to prevent cavities or reduce the swelling of gums. Most research on magnolia has been in laboratories.

Uses

Uses & Effectiveness?

Possibly Effective for

  • Gum inflammation (gingivitis). Chewing gum or using a toothpaste containing magnolia extract seems to reduce the swelling and bleeding of gums.

Insufficient Evidence for

  • Anxiety. Research shows that taking a specific product containing extracts of magnolia plus phellodendron reduces some negative feelings of anxiety caused by stress, such as tension or nervousness. But taking this product doesn't seem to improve long-standing feelings of anxiety due to stress.
  • Dental plaque. Using a toothpaste containing magnolia extract and xylitol might reduce the severity of dental plaque by a small amount.
  • Menopausal symptoms. Early research shows that taking a specific product containing magnolia, soy, and other natural products decreases hot flashes and improves sleep quality compared to taking soy alone.
  • Stress. Early research shows that taking a specific product containing extracts of magnolia plus phellodendron improves mood and decreases stress in people with mental stress.
  • Weight loss. So far, there isn't much evidence that magnolia causes weight loss. There is some research showing that overweight women who take a specific product containing a combination of extracts of magnolia plus phellodendron don't gain as much weight as other women. They seem to eat fewer calories, possibly because the magnolia reduces their stress-related eating. But there is no reliable evidence that taking this product actually causes weight loss.
  • Common cold.
  • Depression.
  • Diabetes.
  • Digestion problems.
  • Facial dark spots.
  • Headache.
  • High cholesterol levels in the blood.
  • Nasal congestion.
  • Runny nose.
  • Toothaches.
  • Other conditions.
More evidence is needed to rate the effectiveness of magnolia for these uses.

Side Effects

Side Effects & Safety

Magnolia is POSSIBLY SAFE for most people when taken by mouth or applied as a toothpaste, short-term. Magnolia has been taken by mouth for up to one year and used in a toothpaste for up to 6 months. Some people may develop skin rashes when magnolia is applied to the skin.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Taking magnolia flower bud by mouth is UNSAFE during pregnancy. There are reports that magnolia can cause the uterus to contract and that might cause a miscarriage. Not enough is known about the safety of using magnolia bark during pregnancy. Stay on the safe side and avoid use.

Not enough is known about the safety of using magnolia during breast-feeding. Stay on the safe side and avoid use.

Surgery: Magnolia can slow down the central nervous system. There is a concern that it might slow down the nervous system too much when combined with anesthesia and other medications used during and after surgery. Magnolia might also slow blood clotting and cause bleeding during and after surgery. Stop using magnolia at least 2 weeks before a scheduled surgery.

Interactions

Interactions?

Moderate Interaction

Be cautious with this combination

!
  • Alcohol interacts with MAGNOLIA

    Alcohol can cause sleepiness and drowsiness. Magnolia bark might also cause sleepiness and drowsiness. Taking large amounts of magnolia bark along with alcohol might cause too much sleepiness.

  • Sedative medications (Barbiturates) interacts with MAGNOLIA

    Magnolia bark might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking magnolia bark along with sedative medications might cause too much sleepiness.<br/><br/> Some sedative medications include amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), and others.

  • Sedative medications (Benzodiazepines) interacts with MAGNOLIA

    Magnolia bark might cause sleepiness and drowsiness. Drugs that cause sleepiness and drowsiness are called sedative medications. Taking magnolia bark along with sedative medications might cause too much sleepiness. Do not take magnolia bark if you are taking sedative medications.<br/><br/> Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.

  • Sedative medications (CNS depressants) interacts with MAGNOLIA

    Magnolia bark might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking magnolia bark along with sedative medications might cause too much sleepiness.<br/><br/> Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

Dosing

Dosing

The following doses have been studied in scientific research:

ADULTS

APPLIED TO THE SKIN:

  • For gingivitis: A toothpaste containing 0.3% magnolia has been used twice daily. Improvements are seen by 3 months. Chewing gum containing magnolia bark extract 0.17% and xylitol 30% has been chewed for 5 minutes three times daily for 30 days.

View References

REFERENCES:

  • Ivie GW, Holt DL, Ivey MC. Natural toxicants in human foods: psoralens in raw and cooked parsnip root. Science 1981;213:909-10.. View abstract.
  • Lutchman, L., Inyang, V., and Hodgkinson, D. Phytophotodermatitis associated with parsnip picking. J.Accid.Emerg.Med. 1999;16(6):453-454. View abstract.
  • Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  • Kawahara, N., Kurata, A., Hakamatsuka, T., Sekita, S., and Satake, M. Two new cucurbitacin glucosides, opercurins A and B, from the Brazilian folk medicine "Buchinha" (Luffa operculata). Chem.Pharm Bull (Tokyo) 2004;52(8):1018-1020. View abstract.
  • Kawahara, N., Kurata, A., Hakamatsuka, T., Sekita, S., and Satake, M. Two novel cucurbitacins, neocucurbitacins A and B, from the Brazilian folk medicine "Buchinha" (Luffa operculata) and their effect on PEBP2alphaA and OCIF gene expression in a human osteoblast-like Saos-2 cell line. Chem.Pharm.Bull.(Tokyo) 2001;49(10):1377-1379. View abstract.
  • Kloss, P. [On the bitter substance from Luffa operculata Cogn.]. Arch Pharm Ber.Dtsch.Pharm Ges. 1966;299(4):351-355. View abstract.
  • Matos, F. D. J. and Gottlieb, O. R. Isocucurbitacine B Cytotoxic Constituant of Luffa Operculata. So Anais Da Acadamia Brasileira De Ciencias 1967;39(2):245.
  • Menon-Miyake, M. A., Carvalho de, Oliveira R., Lorenzi-Filho, G., Saldiva, P. H., and Butugan, O. Luffa operculata affects mucociliary function of the isolated frog palate. Am J Rhinol. 2005;19(4):353-357. View abstract.
  • Menon-Miyake, M. A., Saldiva, P. H., Lorenzi-Filho, G., Ferreira, M. A., Butugan, O., and Oliveira, R. C. Luffa operculata effects on the epithelium of frog palate: histological features. Braz.J Otorhinolaryngol. 2005;71(2):132-138. View abstract.
  • Aguila MB, Sa Silva SP, Pinheiro AR, Mandarim-de-Lacerda CA. Effects of long-term intake of edible oils on hypertension and myocardial and aortic remodelling in spontaneously hypertensive rats. J Hypertens 2004;22:921-9. View abstract.
  • Bardare M, Magnolfi C, Zani G. Soy sensitivity: personal observation on 71 children with food intolerance. Allerg Immunol (Paris) 1988;20:63-6.
  • Drugs in Pregnancy and Lactation. 4th ed. Baltimore, MD: Williams & Wilkins, 1994.
  • Eigenmann PA, Burks AW, Bannon GA, et al. Identification of unique peanut and soy allergens in sera adsorbed with cross-reacting antibodies. J Allergy Clin Immunol 1996;98:969-78. View abstract.
  • Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  • FDA. Center for Science in the Public Interest. A Food Labeling Guide. Available at: http://www.cfsan.fda.gov/~dms/flg-6c.html
  • Fradin MS, Day JF. Comparative efficacy of insect repellents against mosquito bites. N Engl J Med 2002;347:13-8. View abstract.
  • Wang SM, Lee LJ, Huang YT, et al. Magnolol stimulates steroidogenesis in rat adrenal cells. Br J Pharmacol 2000;131:1172-8. View abstract.
  • Yimam M, Jiao P, Hong M, et al. UP601, a standardized botanical composition composed of Morus alba, Yerba mate and Magnolia officinalis for weight loss. BMC Complement Altern Med. 2017;17(1):114. View abstract.
  • Zhong WB, Wang CY, Ho KJ, et al. Magnolol induces apoptosis in human leukemia cells via cytochrome c release and caspase activation. Anticancer Drugs 2003;14:211-7. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.