Lorenzo's oil is used to treat an inherited disorder that affects the nervous system and adrenal glands (adrenoleukodystrophy or ALD), and an inherited condition that affects the spinal cord (adrenomyeloneuropathy or AMN). ALD occurs in children, and AMN occurs in adults.
Lorenzo's oil is named after a child, Lorenzo Odone, who developed ALD. His parents discovered a mixture of fatty acids that seemed to slow progression of the disease. The mixture became known as "Lorenzo's oil."
In the US, Lorenzo's oil is only available to patients participating in a clinical trial.
How does it work ?
Uses & Effectiveness
Possibly Effective for
- An inherited disorder that affects the nervous system and adrenal glands (adrenoleukodystrophy or ALD). Lorenzo's oil might help prevent nervous system problems in children who have ALD, but haven't yet shown any symptoms. Lorenzo's oil probably does not help children who already have symptoms of ALD.
Possibly Ineffective for
- An inherited disorder that affects the spinal cord (adrenomyeloneuropathy or AMN). Taking Lorenzo's oil does not seem to improve symptoms or slow the progression of disease in patients with AMN.
Special Precautions and Warnings
Children: Lorenzo's oil is POSSIBLY SAFE when taken by mouth by children who are under the care of healthcare professionals.
Blood disorders that cause a decrease in blood white cells needed to fight infections (neutropenia): Lorenzo's oil might make this condition worse.
Blood disorders that cause a decrease in blood platelets needed for clotting (thrombocytopenia): Lorenzo's oil might make this condition worse.
We currently have no information for LORENZO'S OIL overview.
- For an inherited disorder that affects the nervous system and adrenal glands (adrenoleukodystrophy or ALD): Lorenzo's oil in a dose of 2-3 mL/kg has been used.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
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© Therapeutic Research Faculty 2020.