Arndt KA, Fitzpatrick TB. Topical use of hydroquinone as a depigmenting agent. JAMA 1965;194(9):965-967. View abstract.
Assaf, M. H., Ali, A. A., Makboul, M. A., Beck, J. P., and Anton, R. Preliminary study of phenolic glycosides from Origanum majorana; quantitative estimation of arbutin; cytotoxic activity of hydroquinone. Planta Med 1987;53(4):343-345. View abstract.
Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225. View abstract.
Chakraborty AK, Funasaka Y, Komoto M, et al. Effect of arbutin on melanogenic proteins in human melanocytes. Pigment Cell Res 1998;11(4):206-212. View abstract.
Grases, F., Melero, G., Costa-Bauza, A., Prieto, R., and March, J. G. Urolithiasis and phytotherapy. Int Urol Nephrol 1994;26(5):507-511. View abstract.
Jin YH, Lee SJ, Chung MH, et al. Aloesin and arbutin inhibit tyrosinase activity in a synergistic manner via a different action mechanism. Arch Pharm Res 1999;22(3):232-236. View abstract.
Kruszewska H, Zareba T, Tyski S. Examination of antimicrobial activity of selected non-antibiotic drugs. Acta Pol Pharm 2004;61 Suppl:18-21. View abstract.
Kubo M, Ito M, Nakata H, et al. [Pharmacological studies on leaf of Arctostaphylos uva-ursi (L.) Spreng. I. Combined effect of 50% methanolic extract from Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) and prednisolone on immuno-inflammation]. Yakugaku Zasshi 1990;110(1):59-67. View abstract.
Larsson B, Jonasson A, Fianu S. Prophylactic effect of UVA-E in women with recurrent cystitis: a preliminary report. Current Therapeutic Research 1993;53(4):441-443.
Maeda K, Fukuda M. Arbutin: mechanism of its depigmenting action in human melanocyte culture. J Pharmacol Exp Ther 1996;276(2):765-769. View abstract.
Matsuda H, Higashino M, Nakai Y, et al. Studies of cuticle drugs from natural sources. IV. Inhibitory effects of some Arctostaphylos plants on melanin biosynthesis. Biol Pharm Bull 1996;19(1):153-156. View abstract.
Nowak AK, Shilkin KB, Jeffrey GP. Darkroom hepatitis after exposure to hydroquinone. Lancet 1995;345(8958):1187. View abstract.
Paper DH, Koehler J, Franz G. Bioavailability of drug preparations containing a leaf extract of Arctostaphylos uva-ursi (L.) Spreng. (Uvae ursi folium). Pharmaceutical and Pharmacological Lett 1993;3:63-66.
Parejo I, Viladomat F, Bastida J, et al. A single extraction step in the quantitative analysis of arbutin in bearberry (Arctostaphylos uva-ursi) leaves by high-performance liquid chromatography. Phytochem Anal 2001;12(5):336-339. View abstract.
Pizzorno J, Murry M. Textbook of Natural Medicine. 1999;989-990, 1187.
Quintus J, Kovar KA, Link P, et al. Urinary excretion of arbutin metabolites after oral administration of bearberry leaf extracts. Planta Med 2005;71(2):147-152. View abstract.
Schindler G, Patzak U, Brinkhaus B, et al. Urinary excretion and metabolism of arbutin after oral administration of Arctostaphylos uvae ursi extract as film-coated tablets and aqueous solution in healthy humans. J Clin Pharmacol 2002;42(8):920-927. View abstract.
Shimizu M, Shiota S, Mizushima T, et al. Marked potentiation of activity of beta-lactams against methicillin-resistant Staphylococcus aureus by corilagin. Antimicrob Agents Chemother 2001;45(11):3198-3201. View abstract.
Sugai T. [Clinical effects of arbutin in patients with chloasma]. Skin Research 1992;34:522-529.
Turi, M., Turi, E., Koljalg, S., and Mikelsaar, M. Influence of aqueous extracts of medicinal plants on surface hydrophobicity of Escherichia coli strains of different origin. APMIS 1997;105(12):956-962. View abstract.
Wahner C, Schonert J, Friedrich H. [Knowledge of the tannin contained in leaves of the bearberry (Arctostaphylos uva-ursi L)]. Pharmazie 1974;29(9):616-617. View abstract.
Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107. View abstract.
de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999.
Larsson B, Jonasson A, Fianu S. Prophylactic effect of UVA-E in women with recurrent cystitis: a preliminary report. Curr Ther Res 1993;53:441-3.
Moore M, Trill J, Simpson C, et al. Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI): a factorial randomized trial. Clin Microbiol Infect. 2019;25(8):973-980. View abstract.
Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. View abstract.
Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. View abstract.