Morera Negra, Morus nigra, Mulberry, Mûrier Noir, Purple Mulberry.<br/><br/>


Overview Information

Black mulberry is a plant. The ripe berry and root bark are used to make medicine.

Black mulberry is used as a laxative and to treat runny nose (rhinitis).

How does it work?

Black mulberry fruit contains pectin, which might act as a laxative to help stool pass through the bowels.


Uses & Effectiveness?

Insufficient Evidence for

More evidence is needed to rate the effectiveness of black mulberry for these uses.

Side Effects

Side Effects & Safety

There isn’t enough information to know whether or not black mulberry is safe.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking black mulberry if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Allergies: People who are allergic to black mulberry might also be allergic to fig.

Diabetes: Black mulberry might lower blood sugar. If you have diabetes, monitor your blood sugar levels closely. The dose of your diabetes medication might need to be changed.

Surgery: Black mulberry seems to lower blood sugar levels. It might interfere with blood sugar control during and after surgery. Stop using black mulberry at least 2 weeks before a scheduled surgery.



Moderate Interaction

Be cautious with this combination

  • Medications for diabetes (Antidiabetes drugs) interacts with BLACK MULBERRY

    Black mulberry leaves might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking black mulberry leaves along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.<br><nb>Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.



The appropriate dose of black mulberry for use as treatment depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for black mulberry. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


  • Caiaffa, M. F., Cataldo, V. M., Tursi, A., and Macchia, L. Fig and mulberry cross-allergy. Ann.Allergy Asthma Immunol. 2003;91(5):493-495. View abstract.
  • de Souza, M. M., Bittar, M., Cechinel-Filho, V., Yunes, R. A., Messana, I., Delle, Monache F., and Ferrari, F. Antinociceptive properties of morusin, a prenylflavonoid isolated from Morus nigra root bark. Z Naturforsch.[C.] 2000;55(3-4):256-260. View abstract.
  • Fu, D. X., Chen, L., Hou, A. J., Yao, Q., and Zhang, W. Y. Constituents of Morus nigra. Chinese Traditional and Herbal Drugs 2005;36
  • Kim, H., Yoon, Y. J., Shon, J. H., Cha, I. J., Shin, J. G., and Liu, K. H. Inhibitory effects of fruit juices on CYP3A activity. Drug Metab Dispos. 2006;34(4):521-523. View abstract.
  • Muntean, D., Imre, S., Avrigeanu, V., and Csedo, C. Physico-chemical study of the isolated flavonoids from leaves and bark of Morus alba L. and Morus nigra L. species. Farmacia 2002;50:97-103.
  • Naderi, G. A., Asgary, S., Sarraf-Zadegan, N., Oroojy, H., and Afshin-Nia, F. Antioxidant activity of three extracts of Morus nigra. Phytother.Res. 2004;18(5):365-369. View abstract.
  • Rabijns, A., Barre, A., Van Damme, E. J., Peumans, W. J., De Ranter, C. J., and Rouge, P. Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose. FEBS J 2005;272(14):3725-3732. View abstract.
  • Rouge, P., Peumans, W. J., Barre, A., and Van Damme, E. J. A structural basis for the difference in specificity between the two jacalin-related lectins from mulberry (Morus nigra) bark. Biochem Biophys.Res Commun. 4-25-2003;304(1):91-97. View abstract.
  • Singh, T., Wu, J. H., Peumans, W. J., Rouge, P., Van Damme, E. J., and Wu, A. M. Recognition profile of Morus nigra agglutinin (Morniga G) expressed by monomeric ligands, simple clusters and mammalian polyvalent glycotopes. Mol Immunol. 3-30-2006. View abstract.
  • Wu, A. M., Wu, J. H., Singh, T., Chu, K. C., Peumans, W. J., Rouge, P., and Van Damme, E. J. A novel lectin (Morniga M) from mulberry (Morus nigra) bark recognizes oligomannosyl residues in N-glycans. J Biomed.Sci 2004;11(6):874-885. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.