Overview
Indian long pepper is used for gastrointestinal problems, lung problems, arthritis, problems during menstruation, and many other conditions, but there is no scientific evidence to support these uses.
Indian long pepper is also used to enhance how well the body absorbs other drugs.
How does it work ?
Uses & Effectiveness ?
Insufficient Evidence for
- Headache.
- Toothache.
- Asthma.
- Arthritis.
- Bronchitis.
- Cholera.
- Memory and thinking skills (cognitive function).
- Coma.
- Cough.
- Diarrhea.
- Epilepsy.
- Fever.
- Heart disease.
- Stomach pain.
- Stroke.
- Indigestion (dyspepsia).
- Menstrual disorders.
- Other conditions.
Side Effects
Special Precautions and Warnings
Bleeding conditions: Indian long pepper might slow blood clotting. In theory, taking Indian long pepper in amounts greater than those in food might increase the risk of bleeding in people with bleeding disorders.
Diabetes: Indian long pepper might affect blood sugar levels. In theory, taking Indian long pepper in amounts greater than those in food might affect blood sugar control in people with diabetes. Dosing adjustments for diabetes medications might be needed.
Surgery: Indian long pepper might slow blood clotting and affect blood sugar levels. In theory, taking Indian long pepper in amounts treater than those found in food might cause bleeding complications or affect blood sugar levels during surgery. You should stop taking Indian long pepper in amounts greater than those in food at least 2 weeks before surgery.
Interactions ?
Phenytoin (Dilantin) interacts with INDIAN LONG PEPPER
Indian long pepper might increase how much phenytoin (Dilantin) the body absorbs. Taking Indian long pepper along with phenytoin (Dilantin) might increase the effects and side effects of phenytoin (Dilantin).
Propranolol (Inderal) interacts with INDIAN LONG PEPPER
Indian long pepper might increase how much propranolol (Inderal) the body absorbs. Taking Indian long pepper along with propranolol (Inderal) might increase the effects and side effects of propranolol (Inderal).
Theophylline interacts with INDIAN LONG PEPPER
Indian long pepper can increase how much theophylline the body absorbs. Taking theophylline along with Indian long pepper might increase the effects and side effects of theophylline.
Cyclosporine (Neoral, Sandimmune) interacts with INDIAN LONG PEPPER
Indian long pepper contains a chemical called piperine. Piperine might increase levels of cyclosporine in the body. In theory, taking Indian long pepper with cyclosporine might increase the effects and side effects of cyclosporine. However, there is not enough known about this potential interaction to know if it is a big concern.
Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates) interacts with INDIAN LONG PEPPER
Some medications are changed and broken down by the liver. Indian long pepper might decrease how quickly the liver breaks down some medications. Taking Indian long pepper along with some medications that are broken down by the liver might increase the chance of side effects from some medications. Before taking Indian long pepper, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include chlorzoxazone, theophylline, and bufuralol.Medications changed by the liver (Cytochrome P450 2B1 (CYP2B1) substrates) interacts with INDIAN LONG PEPPER
Some medications are changed and broken down by the liver. Indian long pepper might decrease how quickly the liver breaks down some medications. Taking Indian long pepper along with some medications that are broken down by the liver might increase the chance of side effects from some medications. Before taking Indian long pepper, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include cyclophosphamide, ifosfamide, barbiturates, bromobenzene, and others.Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with INDIAN LONG PEPPER
Some medications are changed and broken down by the liver. Indian long pepper might decrease how quickly the liver breaks down some medications. Taking Indian long pepper along with some medications that are broken down by the liver might increase the chance of side effects from some medications. Before taking Indian long pepper, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others.Medications for diabetes (Antidiabetes drugs) interacts with INDIAN LONG PEPPER
Indian long pepper contains a chemical called piperine. Some research shows that piperine might decrease blood sugar levels. In theory, Indian long pepper might cause an interaction with diabetes medications resulting in blood sugar levels going too low. Until more is known, monitor your blood sugar closely if you take Indian long pepper. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.Medications moved by pumps in cells (P-glycoprotein substrates) interacts with INDIAN LONG PEPPER
Some medications are moved by pumps in cells. Indian long pepper might make these pumps less active and increase how much of some medications get absorbed by the body. This might cause more side effects from some medications.
Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, digoxin, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with INDIAN LONG PEPPER
Indian long pepper might slow blood clotting. Taking Indian long pepper along with medications that also slow blood clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.Nevirapine (Viramune) interacts with INDIAN LONG PEPPER
Indian long pepper contains a chemical called piperine. Piperine might increase levels of nevirapine in the body. In theory, taking Indian long pepper with nevirapine might increase the effects and side effects of nevirapine. However, there is not enough known about this potential interaction to know if it is a big concern.
Pentobarbital (Nembutal) interacts with INDIAN LONG PEPPER
Indian long pepper contains a chemical called piperine. Piperine might increase sleepiness caused by pentobarbital. In theory, taking Indian long pepper with pentobarbital might increase the sedative side effects of pentobarbital.
Rifampin (Rifadin) interacts with INDIAN LONG PEPPER
Indian long pepper might increase how much rifampin the body absorbs. Taking Indian long pepper along with rifampin might increase the effects and side effects of rifampin.
Moderate Interaction
Be cautious with this combination
Amoxicillin (Amoxil, Trimox) interacts with INDIAN LONG PEPPER
Indian long pepper contains a chemical called piperine. Piperine might increase levels of amoxicillin in the blood. In theory, taking Indian long pepper with amoxicillin might increase the effects and side effects of amoxicillin. However, there is not enough known about this potential interaction to know if it is a big concern.
Carbamazepine (Tegretol) interacts with INDIAN LONG PEPPER
Indian long pepper contains a chemical called piperine. Piperine seems to increase the amount of carbamazepine (Tegretol) absorbed by the body. It seems to also decrease how quickly the body breaks down and gets rid of carbamazepine. Therefore, Indian long pepper might increase how much carbamazepine is in the body and potentially increase the chance of side effects. However, there is not enough known about this potential interaction to know if it is a big concern.
Cefotaxime (Claforan) interacts with INDIAN LONG PEPPER
Indian long pepper contains a chemical called piperine. Piperine might increase levels of cefotaxime in the blood. In theory, taking Indian long pepper with cefotaxime might increase the effects and side effects of cefotaxime. However, there is not enough known about this potential interaction to know if it is a big concern.
Minor Interaction
Be watchful with this combination
Dosing
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