PROPOLIS

OTHER NAME(S):

Acide de Cire d'Abeille, Baume de Propolis, Bee Glue, Bee Propolis, Beeswax Acid, Brazilian Green Propolis, Brazilian Propolis, Brown Propolis, Cire d'Abeille Synthétique, Cire de Propolis, Colle d'Abeille, Green Propolis, Hive Dross, Pénicilline Russe, Propóleos, Propolis Balsam, Propolis Cera, Propolis d'Abeille, Propolis Resin, Propolis Wax, Red Propolis, Résine de Propolis, Russian Penicillin, Synthetic Beeswax, Yellow Propolis.<br/><br/>

Overview

Overview Information

Propolis is a resin-like material made by bees from the buds of poplar and cone-bearing trees. Propolis is rarely available in its pure form. It is usually obtained from beehives and contains bee products. Bees use propolis to build their hives.

Propolis is used for swelling (inflammation) and sores inside the mouth (oral mucositis). It is also used for burns, canker sores, diabetes, genital herpes, cold sores, and other conditions, but there is no good scientific evidence to support these uses.

How does it work?

Propolis seems to have activity against bacteria, viruses, and fungi. It might also have anti-inflammatory effects and help skin heal.

Uses

Uses & Effectiveness?

Possibly Effective for

  • Swelling (inflammation) and sores inside the mouth (oral mucositis). Most research shows that rinsing the mouth with a propolis mouth rinse helps heal sores caused by cancer drugs or dentures.

Insufficient Evidence for

  • Burns. Early research shows that applying propolis to the skin every 3 days might help treat minor burns and prevent infections.
  • Canker sores. Early research shows that taking propolis by mouth daily for 6-13 months reduces canker sore outbreaks.
  • A painful disease transmitted by mosquitos (dengue fever). Research shows that taking propolis helps people with dengue fever leave the hospital faster. It is not known if propolis helps with symptoms of dengue fever.
  • Diabetes. Research shows that taking propolis may slightly improve blood sugar control in people with diabetes. But it doesn't seem to affect insulin levels or improve insulin resistance.
  • Foot sores in people with diabetes. Early research shows that applying a propolis ointment to sores on the feet of people with diabetes might help the sores to heal faster.
  • Genital herpes. Early research shows that applying a 3% propolis ointment four times daily for 10 days might improve healing of lesions in people with genital herpes. Some research suggests that it might heal lesions faster and more completely than the conventional treatment 5% acyclovir ointment.
  • A mild form of gum disease (gingivitis). Early research suggests that using propolis in a gel or a rinse might help prevent or reduce signs of gum disease.
  • A digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori). Early research shows that taking 60 drops of a preparation containing Brazilian green propolis daily for 7 days does not reduce H. pylori infection.
  • Cold sores (herpes labialis). Early research shows that applying ointment containing 0.5% to 3% propolis five times daily improves healing time and reduce pain from cold sores.
  • Infection of the intestines by parasites. Early research suggests that taking a 30% propolis extract for 5 days can cure giardiasis in more people than the drug tinidazole.
  • Thrush. Early research suggests that using Brazilian green propolis extract four times daily for 7 days can prevent oral thrush in people with dentures.
  • A serious gum infection (periodontitis). Early research shows that deeply rinsing the gums with a propolis extract solution decreases bleeding of gums in people with periodontitis. Taking propolis by mouth helps to prevent loose teeth in people with this condition. But taking propolis by mouth doesn't seem to help with plaque or bleeding.
  • Athlete's foot (Tinea pedis). Early research shows that applying Brazilian green propolis to the skin decreases itching, peeling, and redness in students with athlete's foot.
  • Upper airway infection. There is some early evidence that propolis might help prevent or reduce the duration of common colds and other upper airway infections.
  • Swelling (inflammation) of the vagina (vaginitis). Early research suggests that applying a 5% propolis solution vaginally for 7 days can reduce symptoms and improve quality of life in people with vaginal swelling.
  • Warts. Early research shows that taking propolis by mouth daily for up to 3 months cures warts in some people with plane and common warts. However, propolis does not seem to treat plantar warts.
  • Wound healing. Early research shows that using a propolis mouth rinse five times daily for 1 week might improve healing and reduce pain and swelling after mouth surgery. However, if people are already using a special dressing after dental surgery, using a propolis solution in the mouth does not seem to offer additional benefit.
  • Improving immune response.
  • Infections.
  • Inflammation.
  • Nose and throat cancer.
  • Stomach and intestinal disorders.
  • Tuberculosis.
  • Ulcers.
  • Other conditions.
More evidence is needed to rate propolis for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Propolis is POSSIBLY SAFE when taken by mouth appropriately. It can cause allergic reactions, especially in people who are allergic to bees or bee products. Lozenges containing propolis can cause irritation and mouth ulcers.

When applied to the skin: Propolis is POSSIBLY SAFE when applied to the skin appropriately. It can cause allergic reactions, especially in people who are allergic to bees or bee products.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if propolis is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Asthma: Some experts believe certain chemicals in propolis may make asthma worse. Avoid using propolis if you have asthma.

Bleeding conditions: A certain chemical in propolis might slow blood clotting. Taking propolis might increase the risk of bleeding in people with bleeding disorders.

Allergies: Do not use propolis if you are allergic to bee by-products including honey, conifers, poplars, Peru balsam, and salicylates.

Surgery: A certain chemical in propolis might slow blood clotting. Taking propolis might increase the risk of bleeding during and after surgery. Stop taking propolis 2 weeks before surgery.

Interactions

Interactions?

We currently have no information for PROPOLIS Interactions.

Dosing

Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For swelling (inflammation) and sores inside the mouth (oral mucositis): 80 mg of propolis (Natur Farma S.A.S.) 2-3 times daily has been used along with rinsing with bicarbonate solution.
AS A RINSE:
  • For swelling (inflammation) and sores inside the mouth (oral mucositis): 5 mL of propolis 30% mouth rinse (Soren Tektoos) for 60 seconds three times daily for 7 days has been used. 10 mL of a mouth wash has been used as a gargle 3 times daily in addition to chlorhexidine mouthwash and fluconazole for 14 days. Propolis 2% to 3% (extract EPP-AF) has been applied to dentures 3-4 times daily for 7-14 daily.

View References

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  • Szmeja Z, Kulczynski B, Sosnowski Z, Konopacki K. [Therapeutic value of flavonoids in Rhinovirus infections]. Otolaryngol Pol 1989;43:180-4. View abstract.
  • Vynograd N, Vynograd I, Sosnowski Z. A comparative multi-centre study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes (HSV). Phytomedicine 2000;7:1-6. View abstract.
  • Zedan H, Hofny ER, Ismail SA. Propolis as an alternative treatment for cutaneous warts. Int J Dermatol 2009;48(11):1246-9. View abstract.
  • Zhang YX, Yang TT, Xia L, Zhang WF, Wang JF, Wu YP. Inhibitory Effect of Propolis on Platelet Aggregation In Vitro. J Healthc Eng. 2017;2017:3050895. View abstract.
  • Abdel-Fattah, N. S. and Nada, O. H. Effect of propolis versus metronidazole and their combined use in treatment of acute experimental giardiasis. J Egypt.Soc Parasitol. 2007;37(2 Suppl):691-710. View abstract.
  • Al Shaher, A., Wallace, J., Agarwal, S., Bretz, W., and Baugh, D. Effect of propolis on human fibroblasts from the pulp and periodontal ligament. J Endod. 2004;30(5):359-361. View abstract.
  • Almas, K., Mahmoud, A., and Dahlan, A. A comparative study of propolis and saline application on human dentin. A SEM study. Indian J Dent.Res 2001;12(1):21-27. View abstract.
  • Amoros, M., Simoes, C. M., Girre, L., Sauvager, F., and Cormier, M. Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis. J Nat Prod. 1992;55(12):1732-1740. View abstract.

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