Procaine is most often used as an anti-aging agent for conditions such as dementia, age-related decline in memory and thinking skills, quality of life, and many others, but there is no good scientific evidence to support these uses.
As a prescription-only injection, procaine is used for local anesthesia.
How does it work ?
Uses & Effectiveness
- Pain reduction during surgery. Procaine injection is an FDA-approved prescription product used as a local anesthetic.
Insufficient Evidence for
- Decline in memory and thinking skills that occurs normally with age. Early research shows that taking procaine by mouth or as a shot doesn't improve most measures of memory and thinking skills in older people. Also, it might cause side effects.
- Diseases, such as Alzheimer disease, that interfere with thinking (dementia). Early research shows that procaine doesn't improve thinking skills in people with dementia.
- "Hardening of the arteries" in the brain (cerebral atherosclerosis).
- Hair loss.
- High blood pressure.
- Sexual problems.
- Other conditions.
When given as a shot: Procaine is safe when the prescription-only product is given as a shot by a healthcare professional as a local anesthetic.
Special Precautions and Warnings
When given as a shot: Procaine is safe when the prescription-only product is given as a shot by a healthcare professional as a local anesthetic. Pregnancy and breast-feeding: It's LIKELY UNSAFE to use procaine for self-medication if you are pregnant. If you are breast-feeding, it is also best to avoid using procaine. Not enough is known about how it might affect the nursing infant.
Myasthenia gravis, a progressive disease that weakens the muscles: If you have myasthenia gravis, you should not be given procaine intravenously (by IV).
Pseudocholinesterase deficiency, an inherited disorder: People with this disorder are sensitive to certain anesthetic drugs. If you have this disorder, you should not be given procaine by injection.
Systemic lupus erythematosus (SLE): Procaine might make this condition worse. Don't use procaine if you have SLE.
Digoxin (Lanoxin) interacts with PROCAINE
Digoxin (Lanoxin) helps the heart beat more strongly. Digoxin (Lanoxin) can also control how fast the heart beats. Getting a procaine injection can slow the heartbeat. Taking digoxin with procaine might cause your heartbeat to be too slow.
Muscle relaxants interacts with PROCAINE
Procaine is given as a shot to numb pain. Taking procaine with some muscle relaxants can cause the numbing to last too long. Before getting a procaine injection tell your doctor if you are taking any muscle relaxants.
Some of these muscle relaxants include atracurium (Tracrium), pancuronium (Pavulon), succinylcholine (Anectine), and others.
Succinylcholine interacts with PROCAINE
Procaine is injected and used to numb pain. Taking procaine with succinylcholine can cause the numbing to last too long.
Do not take this combination
Aminosalicylic acid interacts with PROCAINE
The body breaks down procaine to get rid of it. Procaine is broken down to a chemical called aminobenzoic acid. Aminobenzoic acid might decrease the effectiveness of aminosalicylic acid. Taking procaine along with aminosalicylic acid might decrease the effectiveness of aminosalicylic acid.
Antibiotics (Sulfonamide antibiotics) interacts with PROCAINE
The body changes procaine to para-aminobenzoic acid (PABA). PABA can decrease the effectiveness of certain antibiotics called sulfonamides.
Some of these antibiotics include sulfamethoxazole (Gantanol), sulfasalazine (Azulfidine), sulfisoxazole (Gantrisin), and trimethoprim/sulfamethoxazole (Bactrim, Septra).
Be cautious with this combination
- For local anesthesia. The prescription-only product is given as a shot by a healthcare professional.
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
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© Therapeutic Research Faculty 2020.