Goldthread is used for digestive disorders, a skin infection caused by Leishmania parasites, a sexually transmitted infection caused by Trichomonas vaginalis, and other conditions, but there is no good scientific evidence to support these uses.
How does it work ?
Uses & Effectiveness
Insufficient Evidence for
Special Precautions and Warnings
Pregnancy: Goldthread is LIKELY UNSAFE during pregnancy. It contains a chemical called berberine that is thought to cross the placenta and may cause harm to the developing child. Brain damage due to too much bilirubin has developed in newborn infants exposed to berberine. Early research suggests pregnant women who take goldthread during the first three months of pregnancy increase the risk that their newborns will have birth defects affecting the central nervous system.
Breast-feeding: Goldthread is LIKELY UNSAFE when taken by mouth by breast-feeding mothers. Berberine and other harmful chemicals in goldthread can be transferred to the infant through breast milk.
Cyclosporine (Neoral, Sandimmune) interacts with GOLDTHREAD
The body breaks down cyclosporine (Neoral, Sandimmune) to get rid of it. Goldthread might decrease how fast the body breaks down cyclosporine (Neoral, Sandimmune). This might cause there to be too much cyclosporine (Neoral, Sandimmune) in the body and potentially cause side effects.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GOLDTHREAD
Some medications are changed and broken down by the liver. Goldthread might decrease how quickly the liver breaks down some medications. Taking goldthread along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking goldthread, talk to your healthcare provider if you are taking any medications that are changed by the liver.
Some medications changed by the liver include cyclosporine (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and many others.
Be cautious with this combination
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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
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© Therapeutic Research Faculty 2020.