Overview

Ornithine ketoglutarate is a salt made from the amino acid ornithine and the glutamine precursor alpha-ketoglutarate. People use it as a medicine.

Ornithine ketoglutarate is taken by mouth to build muscle and increase muscle strength. It is also used for HIV/AIDS and for healing wounds, skinpressure ulcers, and burns.

Ornithine ketoglutarate is sometimes included in nutritional formulas that healthcare providers give as an injection into the veins (intravenously, by IV). Ornithine ketoglutarate is added to the formulas to prevent abnormally slow growth in children who are receiving long-term intravenous feeding.

Ornithine ketoglutarate is also given by IV for helping the body make muscle protein after surgery or stroke; and for treating brain change caused by liver disease. It is also used to reduce nausea and vomiting caused by chemotherapy and improving the health of people that have had a stroke.

Don't confuse ornithine ketoglutarate with ornithine or another chemical called L-ornithine-L-aspartate (LOLA).

How does it work ?

Ornithine ketoglutarate might change the way amino acids, the building blocks of protein, are used in the body. It also increases insulin, a hormone that regulates the amount of sugar in the blood.

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