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Cervical Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for Cervical Cancer

Table 1. Carcinoma of the Cervix Uteria

Stage
a Adapted from FIGO Committee on Gynecologic Oncology.[2]
b All macroscopically visible lesions—even with superficial invasion—are allotted to stage IB carcinomas. Invasion is limited to a measured stromal invasion with a maximal depth of 5.00 mm and a horizontal extension of not >7.00 mm. Depth of invasion should not be >5.00 mm taken from the base of the epithelium of the original tissue—superficial or glandular. The depth of invasion should always be reported in mm, even in those cases with "early (minimal) stromal invasion" (~1 mm).
The involvement of vascular/lymphatic spaces should not change the stage allotment.
c On rectal examination, there is no cancer-free space between the tumor and the pelvic wall. All cases with hydronephrosis or nonfunctioning kidney are included, unless they are known to be the result of another cause.
IThe carcinoma is strictly confined to the cervix (extension to the corpus would be disregarded).
IAInvasive carcinoma, which can be diagnosed only by microscopy with deepest invasion ≤5 mm and largest extension ≥7 mm.
IA1Measured stromal invasion of ≤3.0 mm in depth and extension of ≤7.0 mm.
IA2Measured stromal invasion of >3.0 mm and not >5.0 mm with an extension of not >7.0 mm.
IBClinically visible lesions limited to the cervix uteri or preclinical cancers greater than stage IA.b
IB1Clinically visible lesion ≤4.0 cm in greatest dimension.
IB2Clinically visible lesion >4.0 cm in greatest dimension.
IICervical carcinoma invades beyond the uterus but not to the pelvic wall or to the lower third of the vagina.
IIAWithout parametrial invasion.
IIA1Clinically visible lesion ≤4.0 cm in greatest dimension.
IIA2Clinically visible lesion >4.0 cm in greatest dimension.
IIBWith obvious parametrial invasion.
IIIThe tumor extends to the pelvic wall and/or involves lower third of the vagina and/or causes hydronephrosis or nonfunctioning kidney.c
IIIATumor involves lower third of the vagina with no extension to the pelvic wall.
IIIBExtension to the pelvic wall and/or hydronephrosis or nonfunctioning kidney.
IVThe carcinoma has extended beyond the true pelvis or has involved (biopsy proven) the mucosa of the bladder or rectum. A bullous edema, as such, does not permit a case to be allotted to stage IV.
IVASpread of the growth to adjacent organs.
IVBSpread to distant organs.

References:

  1. Gold MA, Tian C, Whitney CW, et al.: Surgical versus radiographic determination of para-aortic lymph node metastases before chemoradiation for locally advanced cervical carcinoma: a Gynecologic Oncology Group Study. Cancer 112 (9): 1954-63, 2008.
  2. Pecorelli S: Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet 105 (2): 103-4, 2009.
  3. Cervix uteri. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 395-402.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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