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Gastric Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Gastric Cancer

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Stage II

Stage II gastric cancer is divided into stage IIA and stage IIB, depending on where the cancer has spread.

  • Stage IIA: Cancer:
    • has spread to the subserosa (layer of tissue next to the serosa) of the stomach wall; or
    • has spread to the muscle layer of the stomach wall and is found in 1 or 2 lymph nodes near the tumor; or
    • may have spread to the submucosa (layer of tissue next to the mucosa) of the stomach wall and is found in 3 to 6 lymph nodes near the tumor.
  • Stage IIB: Cancer:
    • has spread to the serosa (outermost layer) of the stomach wall; or
    • has spread to the subserosa (layer of tissue next to the serosa) of the stomach wall and is found in 1 or 2 lymph nodes near the tumor; or
    • has spread to the muscle layer of the stomach wall and is found in 3 to 6 lymph nodes near the tumor; or
    • may have spread to the submucosa (layer of tissue next to the mucosa) of the stomach wall and is found in 7 or more lymph nodes near the tumor.

Stage III

Stage III gastric cancer is divided into stage IIIA, stage IIIB, and stage IIIC, depending on where the cancer has spread.

  • Stage IIIA: Cancer has spread to:
    • the serosa (outermost) layer of the stomach wall and is found in 1 or 2 lymph nodes near the tumor; or
    • the subserosa (layer of tissue next to the serosa) of the stomach wall and is found in 3 to 6 lymph nodes near the tumor; or
    • the muscle layer of the stomach wall and is found in 7 or more lymph nodes near the tumor.
  • Stage IIIB: Cancer has spread to:
    • nearby organs such as the spleen, transverse colon, liver, diaphragm, pancreas, kidney, adrenal gland, or small intestine, and may be found in 1 or 2 lymph nodes near the tumor; or
    • the serosa (outermost layer) of the stomach wall and is found in 3 to 6 lymph nodes near the tumor; or
    • the subserosa (layer of tissue next to the serosa) of the stomach wall and is found in 7 or more lymph nodes near the tumor.
  • Stage IIIC: Cancer has spread to:
    • nearby organs such as the spleen, transverse colon, liver, diaphragm, pancreas, kidney, adrenal gland, or small intestine, and may be found in 3 or more lymph nodes near the tumor; or
    • the serosa (outermost layer) of the stomach wall and is found in 7 or more lymph nodes near the tumor.
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