There is no universally agreed upon approach to controlling treatment-resistant depression, also referred to as TRD. Your treatment will depend on your doctor's expertice as well as your own needs, concerns, and medical history.
But while the details may vary, most doctors follow the same basic pattern. Here is a rough outline of how your doctor might treat your depression. If you have treatment-resistant depression, your depression has already typically failed to respond to two or more treatments,...
Create a support team. At first you might want to seek out a few people you know you can really rely on. Don't choose only one person, since that can be overwhelming for them.
Talk to all of them about your depression and what you’ve been feeling. Let them know it's fine to check in on you once in a while to make sure you're doing OK. Or they can help with your treatment by reminding you to take your medicine or by driving you to doctor appointments.
Once you've recovered, your team can help you watch for any signs that your depression might be coming back. They should also have a clear idea of what to do if you have an emergency.
Join a support group. Although they mean well, your family and friends may not understand what you've been through. Some may have their own beliefs about depression that can keep them from giving you the support you need.
If that's the case, think about joining a support group. That way you can meet and talk to people who've had the mood disorder. These connections can help you see that you aren't alone.
Ask your doctor or therapist for the names of groups in your area or for some that meet online. Or get in touch with organizations like the National Alliance on Mental Illness or the Depression and Bipolar Support Alliance.
Think about talking to your co-workers. The decision to open up to them or to your boss about your depression is a complicated one. It's your choice. Legally you don’t have to tell them anything you don't want to. But some people with the mood disorder find that telling certain people at work can be a relief.