If you are:
FDB Contraindicated or Not Recommended: PREMATURE CLOSURE OF DUCTUS ARTERIOSUS, AVOID DURING 3RD TRIMESTER
Precaution: LIMITED DATA SUGGEST LOW AMOUNTS EXCRETED, WITH NO RESULTING EFFECT ON INFANT
No Known Risk: LOW LEVELS IN BREAST MILK, WITH NO KNOWN RESULTING ADVERSE EFFECT ON INFANT
An adult over 60:
management or monitoring precaution: Neuro/Psych-Avoid in older adults with or at high risk of delirium because of inducing or worsening delirium. Avoid in elderly with dementia or cognitive impairment.
management or monitoring precaution: Gastrointestinal-Risk for ulceration or serious GI bleed; highest with history of PUD or GI bleed. Renal-Risk for exacerbation of CKD. Cardiovascular-May exacerbate pre-existing hypertension or CHF. Risk of cardiovascular thrombotic events, including MI and stroke. This risk may occur early in treatment and increases with duration of use. Risk for reinfarction with minimal NSAID use post-MI. Contraindicated with CABG. Hepatic-Elevated hepatic transaminases may occur with chronic use.
Giving ibuprofen-famotidine tablet to a child under 12:
management or monitoring precaution: Safety and efficacy for children less than 6 months not established.