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sirolimus

precautions

What should I know regarding pregnancy, nursing and administering sirolimus to children or the elderly?

If you are:

Pregnant:

FDB Contraindicated or Not Recommended: FDA C; CONTRACEPTION MUST BE STARTED BEFORE TX, DURING TX & FOR 12 WEEKS AFTER

Nursing:

Absolute Contraindication: ANIMAL STUDIES SUGGEST EXCRETION OCCURS;POTENTIAL FOR ADVERSE EFF IN INFANT.

An adult over 60:

Giving sirolimus to a child under 12:

Warning: SAFETY AND EFFICACY NOT ESTABLISHED.

Warning: RENAL FXN IMPAIR., DYSLIPIDEMIA, UTI W/ CONCOMITANT STEROIDS/CALCINEURIN INH

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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