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Side Effects

List sirolimus side effects by likelihood and severity.

The following side effects are associated with sirolimus:

Common side effects of sirolimus:

  • AnemiaSevere
  • Decreased Blood PlateletsSevere
  • Fluid Retention in the Legs, Feet, Arms or HandsSevere
  • High Blood PressureSevere
  • High CholesterolSevere
  • Kidney DiseaseSevere
  • Low Amount of Potassium in the BloodSevere
  • RashSevere
  • Reduction in the Body's Resistance to InfectionSevere
  • Urinary Tract InfectionSevere
  • AcneLess Severe
  • DiarrheaLess Severe
  • Feel Like Throwing UpLess Severe
  • FeverLess Severe
  • Head PainLess Severe
  • High Amount of Triglyceride in the BloodLess Severe
  • Incomplete or Infrequent Bowel MovementsLess Severe
  • Joint PainLess Severe
  • PainLess Severe
  • Stomach CrampsLess Severe
  • Visible Water RetentionLess Severe

Infrequent side effects of sirolimus:

  • Bacterial Infection of the Kidney and Renal PelvisSevere
  • Cyst Containing Lymph FluidSevere
  • Decreased White Blood CellsSevere
  • Syndrome characterized by Anemia and Renal FailureSevere
  • Thrombotic Thrombocytopenic PurpuraSevere
  • Avascular Necrosis of BoneLess Severe
  • NosebleedLess Severe
  • Ovarian CystLess Severe
  • Painful, Red or Swollen MouthLess Severe
  • Problem with PeriodsLess Severe

Rare side effects of sirolimus:

  • A Hernia which Protrudes Into the Abdominal WallSevere
  • A Malignant Pigmented Mole or TumorSevere
  • Acquired Decrease of All Cells in the BloodSevere
  • Allergic Reaction caused by a DrugSevere
  • Allergic Reaction causing Inflammation of Blood VesselsSevere
  • AscitesSevere
  • BK Virus Reactivation causing Kidney ProblemsSevere
  • Blood Clot in Artery of Liver Following Liver TransplantSevere
  • Chest PainSevere
  • Clostridium Difficile Bacteria Related ColitisSevere
  • Decreased Neutrophils a Type of White Blood CellSevere
  • Elevation of Proteins in the UrineSevere
  • Escape of Fluid into the LungsSevere
  • Fluid in the Covering of the Heart or PericardiumSevere
  • Focal Segmental GlomerulosclerosisSevere
  • Giant HivesSevere
  • Hepatitis caused by DrugsSevere
  • High Amount of Potassium in the BloodSevere
  • InfectionSevere
  • Infection caused by a VirusSevere
  • Infection due to unusual MycobacteriaSevere
  • Interstitial PneumonitisSevere
  • Life Threatening Allergic ReactionSevere
  • Liver Tissue DeathSevere
  • Low Amount of Phosphate in the BloodSevere
  • Lung FibrosisSevere
  • Lung Tissue ProblemsSevere
  • Lung Transplant Suture RipSevere
  • Malignant LymphomaSevere
  • Nephrotic SyndromeSevere
  • Obstruction of a Blood Vessel by a Blood ClotSevere
  • PancreatitisSevere
  • PneumoniaSevere
  • Progressive Disease in the White Matter of the BrainSevere
  • Sinus TachycardiaSevere
  • Skin Rash with SloughingSevere
  • Spreading Cancer of Skin's Surface CellsSevere
  • Trouble BreathingSevere
  • Absence of Spermatozoa from the Seminal FluidLess Severe
  • Basal Cell Carcinoma of the SkinLess Severe
  • Impaired Wound HealingLess Severe
  • LymphedemaLess Severe

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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