Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Both atazanavir and indinavir can increase the amount of bilirubin in your blood.
What might happen:
Your skin and the whites of your eyes may turn yellow. You may have abdominal pain.
What you should do about this interaction:
Contact your healthcare professional (e.g. doctor or pharmacist) right away about using these medicines together. Your doctor may want to run some blood test on you. Let your doctor know if you have any yellowing of the eyes or skin or any abdominal pain.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Reyataz (atazanavir sulfate) US prescribing information. Bristol-Myers Squibb Company March, 2015.
2.Reyataz (atazanavir sulfate) Australian product information. Bristol-Myers Squibb Pharmaceuticals January 8, 2004.
3.Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. March, 2015.
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