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Reviewed By: Andrew Seibert,
SOURCES: 2010 Medical Reference from Medstar Television.Kristopher Hunt, MD, Chief Resident, Emergency Medicine, Beth Israel Medical Center, New York.
© 1999-2011 Medstar Television
If you're trying to build muscle, it's likely the topic of creatine (CREE uh teen) has cropped up.
It's only been on the market since the early '90s, and most of the studies point to the fact that it's a relatively benign drug.
Doctor Kristopher Hunt, who uses creatine as a competitive weight lifter, studied whether there are any differences between the two types: creatine monohydrate, or the newer, ethyl ester.
We also had a secondary goal of figuring out what effect both of these supplements have on the kidney, whether it had any effect.
In blood and urine samples, both types boosted a marker doctors use to detect kidney damage… but within 24 hours the levels dropped back to normal. However, that short spike could cause a misdiagnosis.
Which could potentially lead doctors to think that they have a dialyzable situation, that their kidneys, their kidney function is so profoundly abnormal that they may, in fact, need dialysis.
It's a situation fellow doctor and study participant Paul Foster found himself in. He had some routine bloodwork following the creatine study and got a call from his doctor.
He mentioned, you know the creatinine levels are off the roof, what's going on? I'm afraid you might have some kidney damage.
The lesson in all this: if you use this supplement, make sure your doctor knows about it. And, in the case of creatine ethyl ester, Doctor Hunt thinks there's reason to believe it isn't getting to the muscles.
We have some pretty compelling data that creatine ethyl ester may actually get broken down after users ingest it.
Insights that could help build your supplement decision. For WebMD, I'm Sandee Lamotte.
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