Coenzyme Q10 - Topic Overview
Research does not
support a helpful effect of CoQ10 in periodontal (gum) disease, muscular
dystrophy, or exercise recovery.
Is CoQ10 safe?
Taking 100 mg a day or more of CoQ10 has caused mild
insomnia in some people. And research has detected
elevated levels of liver enzymes in people taking doses of 300 mg per day for
long periods of time. Liver toxicity has not been reported.
reported side effects include rashes, nausea, upper abdominal pain, dizziness,
sensitivity to light, irritability, headache, heartburn, and fatigue.
high cholesterol (statins) and medicines that lower
blood sugar cause a decrease of CoQ10 levels and reduce the effects of CoQ10
supplements. CoQ10 can reduce the body's response to the blood thinner (anticoagulant) medicine warfarin (Coumadin) and can
decrease insulin requirements in people with
The U.S. Food and Drug
Administration (FDA) does not regulate dietary supplements in the same way it
regulates medicines. A dietary supplement can be sold with limited or no
research on how well it works or on its safety.
Always tell your
doctor if you are using a dietary supplement or if you are thinking about
combining a dietary supplement with your conventional medical treatment. It may
not be safe to forgo your conventional medical treatment and rely only on a
dietary supplement. This is especially important for women who are pregnant or
When using dietary supplements, keep in mind the
- Like conventional medicines, dietary supplements may cause side
effects, trigger allergic reactions, or interact with prescription and
nonprescription medicines or other supplements you might be taking. A side
effect or interaction with another medicine or supplement may make other health
conditions worse. Always tell your doctor or pharmacist about all dietary
supplements you are taking.
- The way dietary supplements are manufactured may not be
standardized. Because of this, how well they work or any side effects they
cause may differ among brands or even within different lots of the same brand.
The form of supplement that you buy in health food or grocery stores may not be
the same as the form used in research.
- Other than for vitamins and minerals, the long-term effects of
most dietary supplements are not known.