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HIV: Antiretroviral Therapy (ART) - Topic Overview

Antiretroviral therapy (ART) is the combination of several antiretroviral medicines used to slow the rate at which HIV makes copies of itself (multiplies) in the body. A combination of three or more antiretroviral medicines is more effective than using just one medicine (monotherapy) to treat HIV.

The use of three or more antiretroviral medicines-sometimes referred to as an anti-HIV "cocktail"-is currently the standard treatment for HIV infection. So far, this treatment offers the best chance of preventing HIV from multiplying, which allows your immune system to stay healthy. The goal of antiretroviral therapy is to reduce the amount of virus in your body (viral load) to a level that can no longer be detected with current blood tests.

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HIV Medications

Agenerase (amprenavir) Combivir (AZT + 3TC) Complera (Truvada + Edurant) Crixivan (indinavir) Edurant (rilpivirine) Emtriva (emtricitabine) Epivir (lamivudine, "3TC") Fortovase (saquinavir) Fuzeon (enfuvirtide) Hivid (zalcitabine, "ddC") Invirase (saquinavir) Kaletra (lopinavir) Lexiva (fosamprenavir) Norvir (ritonavir) Rescriptor (delavirdine) Retrovir (zidovudine, "AZT") Reyataz (atazanavir) Stribild (Emtriva + Viread + elvitegra...

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Antiretroviral medicines that are often used to treat HIV include:

Some medicines are available combined together in one pill. This reduces the number of pills to be taken each day.

The U.S. National Institutes of Health recommends using one of the following programs for people who begin treatment for HIV:1

  • Efavirenz + tenofovir + emtricitabine
  • Ritonavir-boosted atazanavir + tenofovir + emtricitabine
  • Ritonavir-boosted darunavir + tenofovir + emtricitabine
  • Raltegravir + tenofovir + emtricitabine

Other drug combinations are approved and may be used in some cases.

Also, studies have shown that if you are not infected with HIV, taking antiretroviral medicines can protect you against HIV.2, 3 But to keep your risk low, you still need to use safer sex practices.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: /2, 14 1
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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