Crohn's Disease - Topic Overview
Crohn's disease is a
inflammatory bowel disease (IBD). Parts of the
digestive system get swollen and have deep sores
ulcers. Crohn's disease usually is found in the last
part of the small intestine and the first part of the large intestine. But it
can develop anywhere in the digestive tract, from the mouth to the anus.
Doctors don't know
what causes Crohn's disease. You may get it when the body's
immune system has an abnormal response to normal
bacteria in your intestine. Other kinds of bacteria and viruses may also play a
role in causing the disease.
Crohn's disease can run in families.
Your chances of getting it are higher if a close family member has it. People
of Eastern European (Ashkenazi) Jewish background may have a higher
chance of getting Crohn's disease. Smoking also puts you at a higher risk for
The main symptoms of
Crohn's disease are belly pain and diarrhea (sometimes with blood). Some people
may have diarrhea 10 to 20 times a day. Losing weight without trying is another
common sign. Less common symptoms include mouth sores, bowel blockages, anal
tears (fissures), and openings (fistulas) between organs.
hormonal changes, and smoking can cause your symptoms to flare up. You
may have only mild symptoms or go for long periods of time without any
symptoms. A few people have ongoing, severe symptoms.
important to be aware of signs that Crohn's disease may be getting worse. Call
your doctor right away if you have any of these signs:
- You feel faint or have a fast and weak
- You have severe belly pain.
- You have a fever or
- You are vomiting again and again.
Your doctor will
ask you about your symptoms and do a physical exam. You may also have X-rays
and lab tests to find out if you have Crohn's.
Tests that may be
done to diagnose Crohn's disease include:
- Barium X-rays of the small intestine or
- Colonoscopy or flexible sigmoidoscopy.
In these tests, the doctor uses a thin, lighted tube to look inside the colon.
- Biopsy. The doctor takes a sample of tissue and tests
it to find out if you have Crohn's or another disease, such as
- Stool analysis. This is a test to look for blood and signs
of infection in a sample of your stool.