Crohn's Disease Complications

Medically Reviewed by Minesh Khatri, MD on February 09, 2022

Complications of Crohn's disease may or may not be related to the inflammation within the intestine. Intestinal complications of Crohn's disease include:

  • Obstruction and perforation of the small intestine or colon
  • Sbscesses (collections of pus)
  • Fistulae
  • Intestinal bleeding
  • Kidney stones

Massive distention or dilatation of the colon (megacolon) and rupture (perforation) of the intestine are potentially life-threatening complications. Both may require surgery, but, fortunately, these two complications are rare. Recent data suggest that there is an increased risk of cancer of the small intestine and colon in patients with long-standing Crohn's disease, but studies are conflicting.

Other complications involve the skin, joints, spine, eyes, liver, bones, and bile ducts.

The nutritional deficiencies associated with Crohn's can compromise a child's growth, and can weaken the bones, leading to osteoporosis.