Does Tacrolimus Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • TACROLIMUS/CYCLOSPORINE
  • SELECTED NEPHROTOXIC AGENTS/CIDOFOVIR
  • SELECTED CYP3A4 SUBSTRATES/MIFEPRISTONE
  • SELECT IMMUNOSUPPRESSANTS/OMBITASVIR-PARITAPREVIR-RITONAVIR
  • SELECTED NEPHROTOXIC AGENTS/BACITRACIN
  • SLT IMMUNOSUPPRESSANTS;TEMSIROLIMUS/NIRMATRELVIR-RITONAVIR
  • SELECTED QT PROLONGING AGENTS/SAQUINAVIR
  • SELECTED IMMUNOSUPPRESSANTS/TALIMOGENE LAHERPAREPVEC
  • SELECTED IMMUNOSUPPRESSANTS/TOFACITINIB
  • CALCINEURIN INHIBITORS/MIFAMURTIDE
  • SELECTED IMMUNOSUPPRESSIVE AGENTS/LIVE VACCINES; LIVE BCG
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/EFALIZUMAB; NATALIZUMAB
  • SELECTED QT PROLONGING AGENTS/ZIPRASIDONE
  • SELECTED AGENTS/MIBEFRADIL
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • CYCLOSPORINE; EVEROLIMUS; SIROLIMUS; TACROLIMUS/NSAIDS
  • CYCLOSPORINE;TACROLIMUS/POTASSIUM-SPARING DIURETICS
  • SELECTED IMMUNOSUPPRESSANTS/STRONG CYP3A4 INDUCERS
  • SENSITIVE CYP3A4; CYP2C9; CYP2C19 SUBSTRATES/ENZALUTAMIDE
  • TACROLIMUS/SCHISANDRA CHINENSIS
  • SELECTED NEPHROTOXIC AGENTS/FOSCARNET
  • SELECTED NEPHROTOXIC AGENTS/INOTERSEN
  • TACROLIMUS/DRONEDARONE
  • SELECTED IMMUNOSUPPRESSANTS/CHLORAMPHENICOL
  • SELECT SENSITIVE CYP3A4 SUBSTRATES THAT PROLONG QT/VOXELOTOR
  • SELECTED IMMUNOSUPPRESSANTS/CANNABIDIOL;TETRAHYDROCANNABINOL
  • SELECT SENSITIVE CYP3A4 SUBSTRATES THAT PROLONG QT/TUCATINIB
  • SELECTED CYP3A4 SUBSTRATES/PEXIDARTINIB
  • TACROLIMUS/LONAFARNIB
  • TACROLIMUS/RIBOCICLIB
  • SELECTED CYP3A4 SUBSTRATES/SOTORASIB
  • TACROLIMUS/MOBOCERTINIB
  • SELECTED CYP3A4 SUBSTRATES/MITAPIVAT
  • TACROLIMUS/SELECTED STRONG CYP3A4 INHIBITORS
  • TACROLIMUS/SELECTED STRONG CYP3A4 INHIBITORS THAT PROLONG QT
  • TACROLIMUS/PROTEASE INHIBITORS; COBICISTAT
  • TACROLIMUS/SELECTED AZOLE ANTIFUNGAL AGENTS
  • TACROLIMUS/SELECTED MACROLIDES
  • TACROLIMUS/POSACONAZOLE; VORICONAZOLE
  • TACROLIMUS/PAZOPANIB
  • TACROLIMUS/NICARDIPINE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/CLADRIBINE
  • IMMUNOSUPPRESSIV; IMMUNOMODULATORS THAT PROLONG QT/SIPONIMOD
  • IMMUNOSUPPRESSIVES;IMMUNOMODULATORS THAT PROLONG QT/OZANIMOD
  • IMMUNOSUPPRES;IMMUNOMODULATORS THAT PROLONG QT/FINGOLIMOD
  • IMMUNOSUPPRESSIV;IMMUNOMODULATORS THAT PROLONG QT/PONESIMOD
  • MYELOSUPPRESSIVES; IMMUNOMODULATORS/SODIUM IODIDE I 131
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/FILGOTINIB
  • SELECTED IMMUNOSUPPRESSANTS/LEFLUNOMIDE; TERIFLUNOMIDE
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/BARICITINIB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/INEBILIZUMAB
  • MYELOSUPPRESSIVE AGENTS THAT PROLONG QT/CLOZAPINE
  • POSSIBLE QT PROLONGING AGENTS/HYDROXYCHLOROQUINE
  • P-GP INHIBITORS THAT PROLONG QT/ORAL LEFAMULIN
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/UPADACITINIB
  • POSSIBLE QT PROLONGING AGENTS/DOMPERIDONE
  • IMMUNOSUPPRES;IMMUNOMODUL/SELECTED MULTIPLE SCLEROSIS AGENTS
  • POSSIBLE QT PROLONGING AGENTS/ANAGRELIDE
  • SELECTED MYELOSUPPRESSIVE AGENTS/DEFERIPRONE
  • POSSIBLE QT PROLONGING AGENTS/ARTEMETHER-LUMEFANTRINE
  • SELECTED NEPHROTOXIC AGENTS/COLISTIMETHATE
  • POSSIBLE QT PROLONGING AGENTS/DISOPYRAMIDE
  • POSSIBLE QT PROLONGING AGENTS/CISAPRIDE
  • POSSIBLE QT PROLONGING AGENTS/SERTINDOLE
  • POSSIBLE QT PROLONGING AGENTS/DROPERIDOL
  • POSSIBLE QT PROLONGING AGENTS/LEVOMETHADYL
  • POSSIBLE QT PROLONGING AGENTS/SPARFLOXACIN
  • POSSIBLE QT PROLONGING AGENTS/HALOFANTRINE
  • POSSIBLE QT PROLONGING AGENTS/PIMOZIDE
  • POSSIBLE QT PROLONGING AGENTS/BEPRIDIL
  • TACROLIMUS/SIROLIMUS; TEMSIROLIMUS
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • TACROLIMUS/DANAZOL
  • TACROLIMUS/SELECTED CALCIUM CHANNEL BLOCKERS
  • TACROLIMUS/CASPOFUNGIN
  • TACROLIMUS/SELECTED PROTON PUMP INHIBITORS
  • TACROLIMUS/ERTAPENEM
  • SELECTED NEPHROTOXIC AGENTS/ADEFOVIR
  • SELECTED NEPHROTOXIC AGENTS/IMMUNE GLOBULIN IV (IGIV)
  • TACROLIMUS/MODERATE & WEAK CYP3A4 INHIBITORS THAT PROLONG QT
  • TACROLIMUS/MODERATE AND WEAK CYP3A4 INHIBITORS
  • TACROLIMUS/TIGECYCLINE
  • TACROLIMUS/METOCLOPRAMIDE
  • SELECTED P-GLYCOPROTEIN (P-GP) SUBSTRATES/ABROCITINIB
  • SELECTED IMMUNOSUPPRESSANTS/MARIBAVIR
  • TACROLIMUS/MODERATE AND WEAK CYP3A4 INDUCERS
  • TACROLIMUS/QT PROLONGING AGENTS
  • TACROLIMUS/MODERATE AND WEAK CYP3A4 INDUCERS THAT PROLONG QT
  • QT PROLONGING AGENTS/SAVOLITINIB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/SARILUMAB; TOCILIZUMAB
  • QT PROLONGING AGENTS/TRICLABENDAZOLE
  • POSSIBLE QT PROLONGING AGENTS/PACRITINIB
  • QT PROLONGING AGENTS/TOLTERODINE
  • POSSIBLE QT PROLONGING AGENTS/PANOBINOSTAT
  • QT PROLONGING AGENTS/MIDOSTAURIN
  • SELECTED POSSIBLE QT PROLONGING AGENTS/INTRAVENOUS LEFAMULIN
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/COVID-19 VACCINES
  • POSSIBLE QT PROLONGING AGENTS/FEXINIDAZOLE
  • QT PROLONGING AGENTS/GALANTAMINE
  • POSSIBLE QT PROLONGING AGENTS/LEVOMEPROMAZINE
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/USTEKINUMAB
  • QT PROLONGING AGENTS/SUNITINIB
  • POSSIBLE QT PROLONGING AGENTS/OXALIPLATIN
  • QT PROLONGING AGENTS/AMISULPRIDE
  • QT PROLONGING AGENTS/GILTERITINIB
  • POSSIBLE QT PROLONGING AGENTS/GLASDEGIB
  • POSSIBLE QT PROLONGING AGENTS/IVOSIDENIB
  • POSSIBLE QT PROLONGING AGENTS/ENCORAFENIB
  • POSSIBLE QT PROLONGING AGENTS/TRAZODONE (< 100 MG)
  • POSSIBLE QT PROLONGING AGENTS/LOFEXIDINE
  • POSSIBLE QT PROLONGING AGENTS/MACIMORELIN
  • POSSIBLE QT PROLONGING AGENTS/INOTUZUMAB OZOGAMICIN
  • POSSIBLE QT PROLONGING AGENTS/HYDROXYZINE
  • POSSIBLE QT PROLONGING AGENTS/PIMAVANSERIN
  • TACROLIMUS/COLCHICINE
  • POSSIBLE QT PROLONGING AGENTS/OSIMERTINIB
  • POSSIBLE QT PROLONGING AGENTS/SULPIRIDE
  • POSSIBLE QT PROLONGING AGENTS/PROPOFOL
  • POSSIBLE QT PROLONGING AGENTS/PENTAMIDINE
  • POSSIBLE QT PROLONGING AGENTS/DONEPEZIL
  • POSSIBLE QT PROLONGING AGENTS/CHLORPROMAZINE
  • POSSIBLE QT PROLONGING AGENTS/CHLOROQUINE
  • POSSIBLE QT PROLONGING AGENTS/PROCAINAMIDE
  • POSSIBLE QT PROLONGING AGENTS/IBUTILIDE
  • POSSIBLE QT PROLONGING AGENTS/HYDROQUINIDINE; QUINIDINE
  • POSSIBLE QT PROLONGING AGENTS/FLECAINIDE
  • POSSIBLE QT PROLONGING AGENTS/LENVATINIB
  • POSSIBLE QT PROLONGING AGENTS/DELAMANID
  • QT PROLONGING AGENTS/SEVOFLURANE
  • POSSIBLE QT PROLONGING AGENTS/TRAZODONE (>= 100 MG)
  • QT PROLONGING AGENTS/ESCITALOPRAM
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • POSSIBLE QT PROLONGING AGENTS/BEDAQUILINE
  • QT PROLONGING AGENTS/PASIREOTIDE
  • POSSIBLE QT PROLONGING AGENTS/SORAFENIB
  • QT PROLONGING AGENTS/ALFUZOSIN
  • POSSIBLE QT PROLONGING AGENTS/ONDANSETRON
  • POSSIBLE QT PROLONGING AGENTS/QUETIAPINE
  • POSSIBLE QT PROLONGING AGENTS/CITALOPRAM
  • POSSIBLE QT PROLONGING AGENTS/EZOGABINE
  • POSSIBLE QT PROLONGING AGENTS/VANDETANIB
  • POSSIBLE QT PROLONGING AGENTS/GADOFOSVESET
  • POSSIBLE QT PROLONGING AGENTS/ERIBULIN
  • POSSIBLE QT PROLONGING AGENTS/ROMIDEPSIN
  • POSSIBLE QT PROLONGING AGENTS/ILOPERIDONE
  • POSSIBLE QT PROLONGING AGENTS/TELAVANCIN
  • POSSIBLE QT PROLONGING AGENTS/TOREMIFENE
  • POSSIBLE QT PROLONGING AGENTS/QUININE
  • POSSIBLE QT PROLONGING AGENTS/ZUCLOPENTHIXOL
  • POSSIBLE QT PROLONGING AGENTS/PALIPERIDONE
  • QT PROLONGING AGENTS/DASATINIB
  • SELECTED NEPHROTOXIC AGENTS/TENOFOVIR
  • POSSIBLE QT PROLONGING AGENTS/IVABRADINE
  • POSSIBLE QT PROLONGING AGENTS/MESORIDAZINE
  • QT PROLONGING AGENTS/LEVOFLOXACIN
  • QT PROLONGING AGENTS/HALOPERIDOL
  • QT PROLONGING AGENTS/NORFLOXACIN
  • QT PROLONGING AGENTS/GEMIFLOXACIN
  • POSSIBLE QT PROLONGING AGENTS/LEVOMETHADONE; METHADONE
  • QT PROLONGING AGENTS/APOMORPHINE
  • POSSIBLE QT PROLONGING AGENTS/PROPAFENONE
  • QT PROLONGING AGENTS/DOLASETRON
  • POSSIBLE QT PROLONGING AGENTS/SOTALOL
  • POSSIBLE QT PROLONGING AGENTS/MOXIFLOXACIN
  • QT PROLONGING AGENTS/GATIFLOXACIN
  • POSSIBLE QT PROLONGING AGENTS/DOFETILIDE
  • POSSIBLE QT PROLONGING AGENTS/ARSENIC
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    Drug Survey

    Are you currently using Tacrolimus?

    This survey is being conducted by the WebMD marketing sciences department.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.