Tacrolimus Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • Anemia
  • Blood Disorder
  • Chronic Trouble Sleeping
  • Decreased White Blood Cells
  • Escape Of Fluid Into The Lungs
  • High Amount Of Potassium In The Blood
  • High Blood Sugar
  • Infection
  • Kidney Damage
  • Kidney Disease With Reduction In Kidney Function
  • Low Amount Of Magnesium In The Blood
  • Seizures
  • Toxic Effect On Brain Or Spinal Cord Function

If experienced, these tend to have a Less Severe expression

  • Agitation
  • Confused
  • Constipation
  • Depression
  • Diabetes
  • Diarrhea
  • Dizzy
  • Feel Like Throwing Up
  • Feeling Anxious
  • Feeling Weak
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Hallucination
  • Head Pain
  • Irritation Of The Stomach Or Intestines
  • Itching
  • Loss Of Appetite
  • Nervous
  • Nightmares
  • Numbness And Tingling
  • Rash
  • Shaking Extremities
  • Throwing Up

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • Cushing's Syndrome
  • Disease Of The Muscle Of The Heart With Enlargement
  • High Blood Pressure
  • Infection Caused By A Fungus
  • Low Amount Of Potassium In The Blood
  • Osteoporosis
  • Trouble Breathing

If experienced, these tend to have a Less Severe expression

  • Canker Sore
  • Chest Pain
  • Cramps
  • Disorder Of Nerve
  • Excessive Fat In The Blood
  • Excessive Sweating
  • High Amount Of Triglyceride In The Blood
  • Indigestion
  • Intense Abdominal Pain
  • Pain
  • Problems With Eyesight
  • Ringing In The Ears
  • Swelling Of The Abdomen
  • Urinary Tract Infection

RARE side effects


If experienced, these tend to have a Severe expression

  • A Rupture In The Wall Of The Stomach Or Intestine
  • Abnormal Heart Electrical Signals
  • Abnormal Liver Function Tests
  • Acquired Decrease Of All Cells In The Blood
  • Acute Inflammation Of The Pancreas
  • Angina
  • Atrial Fibrillation
  • Atrial Flutter
  • Basal Cell Carcinoma Of The Skin
  • BK Virus Reactivation Causing Kidney Problems
  • Bleeding
  • Blockage Of A Bile Duct
  • Blood Clot In A Deep Vein Of The Extremities
  • Brain Disease Or Injury Causing Inability To Communicate
  • Brain-Capillary Leak Syndrome
  • Cannot Empty Bladder
  • Chronic Heart Failure
  • Coma
  • Decreased Blood Platelets
  • Decreased Neutrophils A Type Of White Blood Cell
  • Deficiency Of Granulocytes A Type Of White Blood Cell
  • Disease Caused By Cytomegalovirus Infection
  • Disease Of The Optic Nerve
  • Disorder Of Lymphoid Tissue After Transplant
  • Fluid In The Covering Of The Heart Or Pericardium
  • Hemiparesis
  • Hemolytic Anemia
  • Hepatitis
  • Hypertrophic Cardiomyopathy
  • Increase Of White Blood Cells
  • Increased Pressure Of Pulmonary Circulation
  • Infection Caused By A Virus
  • Infection Occurring As A Result Of Having Gallstones
  • Inflammation Of The Bladder With Hemorrhage
  • Inflammation Of The Lining Of The Stomach And Intestines
  • Kidney Failure
  • Left Ventricular Hypertrophy
  • Life Threatening Allergic Reaction
  • Liver Tissue Death
  • Low Platelet Count And Bleeding From Immune Response
  • Lung Embolism
  • Lung Tissue Problems
  • Malignant Lymphoma
  • Paralysis
  • Poor Vision
  • Progressive Disease In The White Matter Of The Brain
  • Prolonged QT Interval On EKG
  • Pure Red Cell Aplasia
  • Rhabdomyolysis
  • Serious Blood Clotting Problem
  • Slow Heartbeat
  • Squamous Cell Carcinoma
  • Stevens-Johnson Syndrome
  • Stomach Ulcer
  • Supraventricular Premature Beats
  • Syndrome Characterized By Anemia And Renal Failure
  • Temporary Blindness
  • Thrombotic Thrombocytopenic Purpura
  • Toxic Epidermal Necrolysis
  • Ventricular Fibrillation
  • Very Rapid Heartbeat - Torsades De Pointes

If experienced, these tend to have a Less Severe expression

  • Altered Mental Status
  • Arthritis
  • Bloody Urine
  • Burning Stomach
  • Delirium
  • Drowsiness
  • Dysarthria
  • Fast Heartbeat
  • Feeling Faint
  • Hearing Loss
  • Hiccups
  • Impaired Wound Healing
  • Inflammation Of The Nose
  • Mood Changes
  • Muscle Pain
  • Pain In Arms Or Legs
  • Problems With Bladder Control
  • Sensitive To Light
  • Skin Darkening
  • Sun-Sensitive Skin
  • The Presence Of Sugar In The Urine

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.