Tacrolimus Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Blood Disorder
  • A Toxic Effect On The Central Nervous System, Which Consists Of The Brain And Spinal Cord
  • An Infection
  • Anemia
  • Damage To The Kidneys
  • Difficulty Sleeping
  • Escape Of Fluid Into The Lungs
  • High Blood Sugar
  • High Levels Of Potassium In The Blood
  • Kidney Disease With Reduction In Kidney Function
  • Low Amount Of Magnesium In The Blood
  • Low Levels Of White Blood Cells
  • Seizures

If experienced, these tend to have a Less Severe expression

  • A Skin Rash
  • Agitation
  • Anxious Feelings
  • Confusion
  • Constipation
  • Decreased Appetite
  • Depression
  • Diabetes
  • Diarrhea
  • Dizziness
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Generalized Weakness
  • Hallucinations
  • Head Pain
  • Irritation Of The Stomach Or Intestines
  • Itching
  • Muscle Tremors
  • Nausea
  • Nervousness
  • Nightmares
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Hormone Disorder Where The Body Produces High Levels Of Cortisol Called Cushing's Syndrome
  • An Infection Due To A Fungus
  • Cardiomyopathy, A Disease Of The Heart Muscle
  • High Blood Pressure
  • Low Amount Of Potassium In The Blood
  • Osteoporosis, A Condition Of Weak Bones
  • Trouble Breathing

If experienced, these tend to have a Less Severe expression

  • A Change In Vision
  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • Canker Sores
  • Chest Pain
  • Cramps
  • Excessive Fat In The Blood
  • Excessive Sweating
  • High Amount Of Triglyceride In The Blood
  • Indigestion
  • Intense Abdominal Pain
  • Numbness
  • Numbness And Tingling
  • Pain
  • Ringing In The Ears
  • Swelling Of The Abdomen
  • Urinary Tract Infection

RARE side effects


If experienced, these tend to have a Severe expression

  • A Clot In The Lung
  • A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis
  • A Rupture In The Wall Of The Stomach Or Intestine
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
  • A Stomach Ulcer
  • A Type Of Blood Clotting Disorder Called Disseminated Intravascular Coagulation
  • A Type Of Blood Disorder Where The Red Blood Cells Burst
  • A Type Of Blood Disorder With A Decrease In All Types Of Blood Cells Called Pancytopenia
  • A Type Of Brain Disorder Called Posterior Reversible Encephalopathy Syndrome
  • Abnormal Heart Electrical Signals
  • Abnormal Liver Function Tests
  • Acute Inflammation Of The Pancreas
  • An Inability To Completely Empty The Bladder
  • An Infection Due To A Virus
  • An Unusual Viral Infection That Can Affect A Part Of The Body Or Spread Called CMV Disease
  • Angina, Or Chest Pain Due To Partial Blockage Of Blood Flow In The Heart Arteries
  • Aphasia, A Loss Of The Ability To Speak And Understand Language
  • Atrial Fibrillation
  • Atrial Flutter
  • Basal Cell Carcinoma Of The Skin
  • Bleeding
  • Blockage Of A Bile Duct
  • Blood Clot In A Deep Vein Of The Extremities
  • Cholangitis, An Infection Resulting From Gallstones
  • Chronic Heart Failure
  • Coma
  • Decreased Blood Platelets
  • Disorder Of Lymphoid Tissue After Transplant
  • Fluid In The Covering Of The Heart Or Pericardium
  • Hemiparesis
  • Hemolytic Uremic Syndrome, A Condition That Affects The Kidney And The Blood
  • High Levels Of White Blood Cells
  • Hypertrophic Cardiomyopathy
  • Inflammation Of The Bladder With Hemorrhage
  • Inflammation Of The Lining Of The Stomach And Intestines
  • Inflammation Of The Liver Called Hepatitis
  • Kidney Failure
  • Kidney Problems Due To BK Polyomavirus
  • Left Ventricular Hypertrophy
  • Liver Tissue Death
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Low Platelet Count And Bleeding From Immune Response
  • Lung Tissue Problems
  • Malignant Lymphoma
  • Optic Neuropathy, A Disease Of The Optic Nerve
  • Paralysis
  • Progressive Multifocal Leukoencephalopathy, A Type Of Brain Infection
  • Prolonged QT Interval On EKG
  • Pulmonary Hypertension
  • Pure Red Cell Aplasia
  • Slow Heartbeat
  • Squamous Cell Carcinoma
  • Supraventricular Premature Beats
  • Temporary Blindness
  • Thrombotic Thrombocytopenic Purpura, A Type Of Blood Disorder
  • Torsades De Pointes, A Type Of Abnormal Heart Rhythm
  • Ventricular Fibrillation, A Heart Rhythm Disorder
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell
  • Vision Loss

If experienced, these tend to have a Less Severe expression

  • A Condition Where There Is Excess Sugar In The Urine
  • A Type Of Speech Disorder Called Dysarthria
  • A Type Of Stomach Irritation Called Gastritis
  • Arthritis
  • Bloody Urine
  • Darkening Of The Skin
  • Delirium
  • Drowsiness
  • Fainting
  • Fast Heartbeat
  • Hearing Loss
  • Hiccups
  • Impaired Wound Healing
  • Increased Sensitivity Of The Skin To The Sun
  • Inflammation Of The Nose
  • Involuntary Leakage Of Urine
  • Mental Status Changes
  • Mood Changes
  • Muscle Pain
  • Pain In The Arms Or Legs
  • Visual Sensitivity To Light

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.