Warnings:

Aldesleukin must be given in a hospital setting by a health care professional. It must be used with extreme caution in patients with heart or lung problems.

Rarely, this medication can cause capillary leak syndrome (CLS), a serious condition that can sometimes be fatal. If you develop any of the following signs of CLS, tell your doctor right away: swelling, severe dizziness, fainting, irregular heartbeat, chest pain (angina), trouble breathing, signs of kidney problems (such as change in the amount of urine), mental/mood changes, severe stomach/abdominal pain, black stools.

Aldesleukin can also make you more likely to get serious infections. Before using this drug, tell your doctor if you currently have any infections. Also, tell your doctor right away if you develop any of the following signs of infection: persistent sore throat, fever.

Rarely, this drug may cause a loss of consciousness. If this drug makes you unusually sleepy, stop using it and tell your doctor right away.

Uses

Aldesleukin is used to treat kidney or skin cancer. This medication is the same as a substance that your body normally makes (interleukin-2). In the body, this drug is thought to work by affecting the body's natural defenses (immune system). This effect slows or stops cancer cell growth.

How to use Aldesleukin Solution, Reconstituted (Recon Soln)

This medication is given by injection into a vein over 15 minutes by a health care professional. It may also be given in other ways as directed by your doctor.

This medication is usually given every 8 hours for 5 days in a row. However, your doctor may decide to delay or stop your treatment depending on how you respond to this drug. After this treatment period, you will be given time to rest and recover before getting more of this medication. A course of therapy may include up to 28 doses of this medication. To make sure that you receive each scheduled dose as directed, it is important to keep all of your medical appointments while receiving this medication. Depending on your response, your doctor may decide that a second course would be helpful.

Dosage is based on your medical condition, weight, response to treatment, and your side effects.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.