Who should not take Indomethacin Suppository?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • systemic mastocytosis
  • cancer of large intestine
  • high amount of potassium in the blood
  • increased risk of bleeding due to clotting disorder
  • psychotic disorder
  • depression
  • parkinson symptoms
  • blurred vision
  • deposits on the eye
  • high blood pressure
  • heart attack
  • chronic heart failure
  • stroke
  • blood clot
  • hemorrhoids
  • asthma
  • painful
  • red or swollen mouth
  • ulcer of the duodenum
  • stomach or intestinal ulcer
  • ulcerated colon
  • blood coming from anus
  • inflammation of the rectum
  • liver problems
  • bleeding of the stomach or intestines
  • seizures
  • abnormal liver function tests
  • pregnancy
  • a rupture in the wall of the stomach or intestine
  • Increased Cardiovascular Event Risk
  • Time Immediately after Coronary Bypass Surgery
  • Diverticular Disease
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)
  • kidney disease with likely reduction in kidney function
  • aspirin exacerbated respiratory disease


  • Salicylates
  • NSAIDS (Non-Steroidal Anti-Inflammatory Drug)

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.