TASIGNA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low amount of calcium in the blood
  • low amount of sodium in the blood
  • high levels of potassium in the blood
  • low amount of potassium in the blood
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • anemia
  • decreased blood platelets
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • high blood pressure
  • prolonged QT interval on EKG
  • a skin rash
  • high amount of bilirubin in the blood
  • high blood sugar
  • high blood levels of the lipase enzyme

If experienced, these tend to have a Less Severe expression i

  • low amount of phosphate in the blood
  • throat irritation
  • a common cold
  • constipation
  • urinary tract infection
  • itching
  • joint pain
  • backache
  • muscle spasm
  • muscle pain
  • sensation of spinning or whirling
  • fever
  • low energy
  • pain
  • visible water retention
  • temporary redness of face and neck
  • decreased appetite
  • headache
  • heart throbbing or pounding
  • cough
  • nausea
  • vomiting
  • diarrhea
  • stomach cramps
  • generalized weakness
  • a feeling of general discomfort called malaise
  • night sweats

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • low amount of magnesium in the blood
  • a decreased number of lymphocytes in the blood
  • a change in vision
  • bleeding in the eye
  • abnormal heart electrical signals
  • bleeding within the skull
  • bleeding
  • the flu
  • escape of fluid into the lungs
  • bleeding of the stomach or intestines
  • hives
  • trouble breathing
  • abnormal liver function tests
  • pancreatitis
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • water retention
  • depression
  • pink eye
  • dry eye
  • indigestion
  • a type of skin condition with redness and itching called eczema
  • inflammation of the skin due to an allergy
  • erythema or redness of skin or mucous membrane
  • hair loss
  • inflammation of a hair follicle
  • acne
  • dry skin
  • muscle weakness
  • bone pain
  • dizziness
  • difficulty sleeping
  • excessive sweating
  • taste impairment
  • numbness
  • a change in voice
  • nosebleed
  • gas
  • an increased need to urinate often
  • abdominal bloating
  • bruising
  • a feeling of pins and needles on skin
  • low energy and weakness
  • chest pains unrelated to heart problems
  • a small, soft skin growth called cutaneous papilloma
  • pain in the muscles or bones
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • an infection
  • thyroid gland inflammation
  • low blood sugar
  • fluid accumulation in the brain
  • fluid accumulation around the eye
  • sudden blindness and pain upon moving the eye
  • hearing loss
  • a heart attack
  • angina, a type of chest pain
  • a low supply of oxygen rich blood to the heart
  • fluid in the covering of the heart or pericardium
  • atrioventricular block, a type of slow heart rhythm disorder
  • atrial fibrillation
  • atrial flutter
  • extra heartbeats
  • slow heartbeat
  • heart failure
  • cerebral ischemia, a lack of blood supply to the brain
  • a blood clot
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • pneumonia
  • fluid in the lungs
  • acute liver failure
  • inflammation of the liver called hepatitis
  • a condition where the body is unable to maintain adequate blood flow called shock
  • chest pain
  • ascites
  • reactivation of hepatitis B infection
  • peripheral arterial occlusive disease
  • paralysis of nerves for the face
  • hardening of the arteries
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

  • an infection due to the fungus Candida
  • ringing in the ears
  • an earache
  • chills
  • puffy face from water retention
  • involuntary leakage of urine
  • hematoma, a collection of blood outside of the blood vessels
  • restless legs syndrome, an extreme discomfort in the calf muscles when sitting or lying down
  • fast heartbeat

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.