Who should not take MEKINIST?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • an increased risk of bleeding
  • detachment of the retina of the eye
  • a blockage of blood vessels in the retina of the eye
  • a clot in the lung
  • cardiomyopathy, a disease of the heart muscle
  • chronic heart failure
  • blood clot in a deep vein of the extremities
  • a body temperature higher than 101 degrees Fahrenheit
  • high blood sugar
  • pregnancy
  • a mother who is producing milk and breastfeeding
  • a rupture in the wall of the stomach or intestine
  • lung tissue problem
  • a blood clot in a retinal vein

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.