CHLORDIAZEPOXIDE-AMITRIPTYLINE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • muscle weakness

If experienced, these tend to have a Less Severe expression i

  • indigestion
  • drowsiness
  • inducing of a relaxed easy state
  • dizziness
  • loss of muscle coordination
  • slurred speech
  • dry mouth
  • weight gain
  • increased hunger
  • headache

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • confusion
  • behavioral problems
  • abnormal nervous system function affecting alertness
  • slow heartbeat
  • abnormal heart rhythm
  • low blood pressure
  • an inability to completely empty the bladder

If experienced, these tend to have a Less Severe expression i

  • low energy
  • diarrhea
  • generalized weakness
  • over excitement
  • altered interest in having sexual intercourse
  • constipation
  • difficulty concentrating
  • difficulty sleeping
  • excessive sweating
  • taste impairment
  • vomiting
  • heartburn
  • nervousness

RARE side effects

If experienced, these tend to have a Severe expression i

  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • low blood counts due to bone marrow failure
  • anemia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • increased eosinophils in the blood
  • high levels of white blood cells
  • mental problems from taking the drug
  • manic behavior
  • suicidal thoughts
  • addiction to a drug
  • depression
  • feelings of hostility
  • low blood pressure
  • decreased lung function
  • coma
  • memory loss
  • hallucinations
  • seizures
  • a skin rash
  • apnea, a breathing interruption
  • trouble breathing
  • an inability to completely empty the bladder
  • abnormal liver function tests
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • accidental falls
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • sleepwalking
  • a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone
  • large purple or brown skin blotches
  • tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue
  • extrapyramidal disease, a type of movement disorder
  • serotonin syndrome, a type of disorder with high serotonin levels
  • increased pressure in the eye
  • a heart attack
  • a type of slowed heart rhythm disorder called heart block
  • abnormal heart electrical signals
  • rapid ventricular heartbeat
  • ventricular fibrillation, a heart rhythm disorder
  • sinus tachycardia, a type of fast heart rate
  • prolonged QT interval on EKG
  • a stroke
  • inflammation of the liver called hepatitis
  • increased sensitivity of the skin to the sun
  • swelling of the tongue
  • slurred speech
  • secondary angle-closure glaucoma, a type of eye disorder
  • fast heartbeat

If experienced, these tend to have a Less Severe expression i

  • over excitement
  • depersonalization, a disconnection of one's own sense of reality or identity
  • altered interest in having sexual intercourse
  • nightmares
  • agitation
  • aggressive behavior
  • double vision
  • blurred vision
  • a change in vision
  • pink eye
  • nystagmus, a condition with involuntary eye movements
  • excessive saliva production
  • dry mouth
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • a painful, red or swollen tongue
  • constipation
  • a problem with menstrual periods
  • itching
  • hair loss
  • cramps
  • difficulty concentrating
  • fainting
  • sensation of spinning or whirling
  • a sleep disorder
  • muscle tremors
  • decreased appetite
  • excessive thirst
  • headache
  • a type of speech disorder called dysarthria
  • yawning
  • hiccups
  • nausea
  • difficult or painful urination
  • involuntary leakage of urine
  • nervousness
  • irritability
  • complex sleep behaviors like eating or driving while asleep
  • abnormal dreams
  • problems thinking clearly
  • fast heartbeat
  • delusions
  • feelings of hostility
  • disturbance in the ability of the eye to focus
  • dilated pupils
  • high blood pressure
  • inflammation of the parotid gland
  • a discolored tongue
  • loss of muscle coordination
  • weight loss
  • heart throbbing or pounding
  • a feeling of pins and needles on skin
  • an inability to control impulsive behavior
  • anxious feelings

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.