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    Imatinib MESYLATE

    precautions

    What should I know regarding pregnancy, nursing and administering Imatinib MESYLATE to children or the elderly?

    If you are:

    Pregnant:

    Not Recommended: BASED ON DRUG PHARMACOLOGY DEVELOPMENTAL TOXICITY IS POSSIBLE

    Nursing:

    Absolute Contraindication: CAUTION ADVISED; POTENTIAL SERIOUS EFFECTS ON INFANT

    An adult over 60:

    management or monitoring precaution: Cardiovascular-Greater risk of edema. Monitor patients with underlying CHF, establish baseline left ventricular function. Renal-Adjust dose for mild to moderate renal impairment. Increased risk of renal toxicity with prolonged therapy.

    Giving imatinib MESYLATE to a child under 12:

    Severe Precaution: Reports of slowed growth rate. No safety and efficacy data age < 1 year.

    management or monitoring precaution: Monitor closely for slowed growth rate.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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