INDOMETHACIN Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • water retention
  • visible water retention
  • an intense headache
  • abnormal liver function tests

If experienced, these tend to have a Less Severe expression i

  • indigestion
  • dizziness
  • headache
  • nausea
  • upper abdominal pain

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • ringing in the ears
  • bleeding
  • stomach or intestinal ulcer
  • itching
  • fainting
  • a skin rash

If experienced, these tend to have a Less Severe expression i

  • stomatitis, a condition with painful swelling and sores inside the mouth
  • constipation
  • drowsiness
  • excessive sweating
  • temporary redness of face and neck
  • decreased appetite
  • vomiting
  • diarrhea

RARE side effects

If experienced, these tend to have a Severe expression i

  • high levels of potassium in the blood
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • decreased function of bone marrow
  • low blood counts due to bone marrow failure
  • anemia
  • a type of blood clotting disorder called disseminated intravascular coagulation
  • a decrease in platelet clotting
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • increased eosinophils in the blood
  • mental problems from taking the drug
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • double vision
  • blurred vision
  • deposits on the eye
  • high blood pressure
  • a heart attack
  • abnormal heart rhythm
  • chronic heart failure
  • a stroke
  • thrombophlebitis, an inflamed vein due to a blood clot
  • low blood pressure
  • bruising under the skin
  • fluid in the lungs
  • bronchospasm
  • inflammation of the esophagus
  • an ulcer in the esophagus
  • a stomach ulcer
  • an ulcer from too much stomach acid
  • inflammation of the large intestine
  • inflammation of the lining of the stomach and intestines
  • blood coming from anus
  • inflammation of the rectum
  • inflammation of the liver called hepatitis
  • bleeding of the stomach or intestines
  • nephrotic syndrome, a type of kidney disorder
  • a type of kidney inflammation called interstitial nephritis
  • damage to the kidneys
  • kidney failure
  • renal papillary necrosis
  • decreased kidney function
  • bloody urine
  • bleeding not related to menstrual period
  • inflammation of the skin due to an allergy
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • skin rash with sloughing
  • hives
  • seizures
  • a type of speech disorder called dysarthria
  • nosebleed
  • trouble breathing
  • chest pain
  • bloody vomit
  • abdominal bloating
  • elevation of proteins in the urine
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a rupture in the wall of the stomach or intestine
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • pancreatitis

If experienced, these tend to have a Less Severe expression i

  • large purple or brown skin blotches
  • enlarged breasts
  • breast pain
  • hair loss
  • muscle weakness
  • difficulty sleeping
  • fever
  • low energy
  • small reddish-purplish pin-point sized spots on skin
  • weight gain
  • heart throbbing or pounding
  • gas
  • an increased need to urinate often
  • high blood sugar
  • a condition where there is excess sugar in the urine
  • nervousness
  • involuntary muscle movements
  • anxious feelings
  • fast heartbeat

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.