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What medications can cause tooth discoloration?

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These antibiotics can cause brown, yellow-brown, or gray tooth discoloration:

  • Amoxicillin-clavulanate (Augmentin), used to treat bacterial infections
  • Chlorhexidine, an antiseptic/disinfectant
  • Doxycycline, used to treat acne
  • Tetracycline, used to treat acne and some respiratory infections

These antibiotics may cause greenish or a blue-green grayish color:

  • Ciprofloxacin (Cipro)
  • Minocycline

Too much fluoride can lead to white streaks on the tooth enamel, or a whitish-brown discoloration.

Iron salts taken by mouth can lead to black teeth.

SOURCES:

American Heart Association: "Possible Side Effects of Drugs That Lower Blood Pressure." 

Cancer Research UK: "Types and Causes of Mouth Problems."

American Academy of Periodontology: "How to Keep a Healthy Smile for Life."

Cancer Research UK: "Types and Causes of Mouth Problems." 

Academy Of General Dentistry: "Treatments For Depression Have Dental Side Effects."

Journal of the American Dental Association, June 2005.

Rees, T.D. Periodontology 2000, October1998.

Heidelbaugh, J. Clinical Men's Health: Evidence in Practice, 1st ed. Philadelphia, Elsevier, 2007.

Duthie, E.H. Practice of Geriatrics, 4th ed. Philadelphia, Elsevier, 2007.

Walsh, D. Palliative Medicine, 1st ed. Philadelphia, Saunders, 2008.

MedlinePlus: "Mouth sores."

Ciancio, S. Journal of the American Dental Association, vol 135.

Nelson, R. Archives of Dermatology. August 2006.

American Pregnancy Association: "Acne treatment during pregnancy."

MedlinePlus: "Tetracycline."

National Institutes of Health: "Taste Disorders."

Padala, K.P. Primary Care Companion Journal of Clinical Psychiatry, 2006.

Reviewed by Alfred D. Wyatt Jr. on August 11, 2020

SOURCES:

American Heart Association: "Possible Side Effects of Drugs That Lower Blood Pressure." 

Cancer Research UK: "Types and Causes of Mouth Problems."

American Academy of Periodontology: "How to Keep a Healthy Smile for Life."

Cancer Research UK: "Types and Causes of Mouth Problems." 

Academy Of General Dentistry: "Treatments For Depression Have Dental Side Effects."

Journal of the American Dental Association, June 2005.

Rees, T.D. Periodontology 2000, October1998.

Heidelbaugh, J. Clinical Men's Health: Evidence in Practice, 1st ed. Philadelphia, Elsevier, 2007.

Duthie, E.H. Practice of Geriatrics, 4th ed. Philadelphia, Elsevier, 2007.

Walsh, D. Palliative Medicine, 1st ed. Philadelphia, Saunders, 2008.

MedlinePlus: "Mouth sores."

Ciancio, S. Journal of the American Dental Association, vol 135.

Nelson, R. Archives of Dermatology. August 2006.

American Pregnancy Association: "Acne treatment during pregnancy."

MedlinePlus: "Tetracycline."

National Institutes of Health: "Taste Disorders."

Padala, K.P. Primary Care Companion Journal of Clinical Psychiatry, 2006.

Reviewed by Alfred D. Wyatt Jr. on August 11, 2020

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Can fluoride cause tooth discoloration?

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