INDOLE-3-CARBINOL: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

Indole-3-carbinol is formed from a substance called glucobrassicin found in vegetables such as broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas. Indole-3-carbinol is formed when these vegetables are cut, chewed or cooked. It can also be produced in the laboratory.

People use indole-3-carbinol for cancer prevention, to treat systemic lupus erythematosus (SLE), and for many other conditions, but there is no good scientific evidence to support these uses.

How does it work ?

There is interest in indole-3-carbinol for cancer prevention, particularly breast, cervical, and colon cancer, because diets with higher amounts of fruits and vegetables are linked to a decreased risk of these cancers. Indole-3-carbinol is present in several vegetables and might help protect against cancer.

View References

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

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INDOLE-3-CARBINOL

Overview

How does it work ?

Uses & Effectiveness ?

Insufficient Evidence for

Side Effects

Special Precautions and Warnings

Interactions ?

Moderate Interaction

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with INDOLE-3-CARBINOL

Dosing

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