Alanyl-L-Histidine, B-Alanyl-L-Histidine, B-Alanyl Histidine, Beta-alanyl-L-histidine, Bêta-Alanyl-L-Histidine, Carnosina, L-Carnosine, Levo-Carnosine, N-Acetyl-Carnosine, N-Acétyl-Carnosine, N-Acetyl-L-Carnosine, N-Acétyl-L-Carnosine.


Overview Information

Carnosine is a protein building block that is naturally produced in the body. It is found in muscles when they are working, and it is also found in the heart, brain, and many other parts of the body.

Carnosine is used by mouth to prevent signs of aging, for diabetes, and many other conditions, but there is no good scientific evidence to support these uses.

How does it work?

Carnosine is important for many normal body functions including the proper function and development of the muscles, heart, liver, kidneys, brain, and many other organs. There is some interest in using carnosine to prevent aging because it seems to interfere with certain chemicals that might play a role in the aging process.


Uses & Effectiveness?

Insufficient Evidence for

  • Autism. Early research shows that taking L-carnosine by mouth for 8 weeks may improve symptoms in children with autism. But not all research agrees.
  • Heart failure. Taking carnosine by mouth for 6 months might help people with heart failure walk farther by helping the body take in more oxygen. This might also make people feel happier.
  • A group of symptoms experienced by people fighting in the Gulf War (Gulf War illness). Taking carnosine along with other medicine by mouth does not improve most symptoms of this disease, like tiredness and pain. However, it might improve symptoms of irritable bowel syndrome, such as diarrhea. Also, it might help memory by a small amount.
  • A type of anxiety marked by recurrent thoughts and repetitive behaviors (obsessive-compulsive disorder or OCD). Early research shows that taking carnosine twice daily by mouth for 10 weeks with the prescription drug fluvoxamine might reduce symptoms of repetition by a small amount in people with moderate to severe OCD.
  • Bed sores (pressure ulcers). Taking carnosine alone or with zinc by mouth might help to speed up the healing of pressure ulcers.
  • Schizophrenia. Taking carnosine by mouth does not seem to make people with schizophrenia feel happier. However, it might help to improve memory.
  • Diabetes.
  • Decline in memory and thinking skills that occurs normally with age.
  • Athletic performance.
  • Aging.
  • Complications of diabetes.
  • Dry skin.
  • Glaucoma.
  • Obesity.
  • Ulcerative colitis.
  • Other conditions.
More evidence is needed to rate the effectiveness of carnosine for these uses.

Side Effects

Side Effects & Safety

When taken by mouth: Carnosine is POSSIBLY SAFE for most children and adults. However, there can be some rare side effects. These might include dry mouth, changes in appetite, feelings of tiredness, or vivid dreams.

When applied to the skin: Carnosine is POSSIBLY SAFE for most adults. However, there can be some rare side effects. These might include a rash or itchiness.

When given as an enema (rectally): Carnosine is POSSIBLY SAFE for most adults when used as an enema.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if carnosine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Low blood pressure: Carnosine might lower blood pressure. In theory, taking carnosine might make blood pressure become too low in people with low blood pressure.


We currently have no information for CARNOSINE Interactions.



The appropriate dose of carnosine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for carnosine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References


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