BANABA

OTHER NAME(S):

Banaba Extract, Banabalean, Corosolic acid, Crape Myrtle, Crepe Myrtle, Extrait de Banaba, Lagerstroemia flos-reginae, Lagerstroemia speciosa, Munchausia speciosa, Myrte de Crêpe, Pride-of-India, Pyinma, Queen's Crape Myrtle.<br/><br/>

Overview

Overview Information

Banaba is a species of crepe myrtle tree that is native to the Philippines and Southeast Asia. People use the leaves to make medicine.

Banaba is used for diabetes and weight loss.

How does it work?

Banaba seems to lower blood glucose in people with type 2 diabetes, according to very early research. It might help the body use insulin more efficiently.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Diabetes. Some early research suggests that taking a particular banaba extract (Glucosol) for 2 weeks lowers blood sugar by 10% in people with type 2 diabetes. However, other early research suggests that taking a single dose of corosolic acid, a chemical in banaba, before eating does not improve post-meal sugar tolerance.
  • Weight loss.
  • Other conditions.
More evidence is needed to rate the effectiveness of banaba for these uses.

Side Effects

Side Effects & Safety

Banaba is POSSIBLY SAFE for most people when taken by mouth on a short-term basis. Not enough is known about the safety of using banaba long term.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of banaba during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Diabetes: Banaba can affect blood sugar control, so people with diabetes should monitor their blood glucose levels closely. If you have diabetes, it's best to check with your healthcare provider before starting banaba.

Low blood pressure. Banaba might lower blood pressure. In theory, taking banaba might make blood pressure become too low in people with low blood pressure.

Surgery: Banaba might affect blood sugar levels and could make blood sugar control more difficult during and after surgery. Stop using banaba at least 2 weeks before a scheduled surgery.

Interactions

Interactions?

Moderate Interaction

Be cautious with this combination

!
  • Medications for diabetes (Antidiabetes drugs) interacts with BANABA

    Banaba might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking banaba along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.<br/><br/> Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Dosing

Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For diabetes: A specific banaba extract has been taken at a dose of 32-48 mg per day for 2 weeks. A specific product containing a combination of banaba and cinnamon inner bark has been taken at a dose of 100 mg per day for 12 weeks.

View References

REFERENCES:

  • Fukushima, M., Matsuyama, F., Ueda, N., Egawa, K., Takemoto, J., Kajimoto, Y., Yonaha, N., Miura, T., Kaneko, T., Nishi, Y., Mitsui, R., Fujita, Y., Yamada, Y., and Seino, Y. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res Clin Pract 2006;73(2):174-177. View abstract.
  • Garcia, L. L et al. Pharmaceutico-chemical and pharmacological studies on a crude drug from Lagerstroemia speciosa (L.) Pers. Philippine J Sci 1987;116:361-375.
  • Khan, M. T., Lampronti, I., Martello, D., Bianchi, N., Jabbar, S., Choudhuri, M. S., Datta, B. K., and Gambari, R. Identification of pyrogallol as an antiproliferative compound present in extracts from the medicinal plant Emblica officinalis: effects on in vitro cell growth of human tumor cell lines. Int.J.Oncol. 2002;21(1):187-192. View abstract.
  • Lampronti, I., Khan, M. T., Bianchi, N., Ather, A., Borgatti, M., Vizziello, L., Fabbri, E., and Gambari, R. Bangladeshi medicinal plant extracts inhibiting molecular interactions between nuclear factors and target DNA sequences mimicking NF-kappaB binding sites. Med Chem 2005;1(4):327-333. View abstract.
  • Yamaguchi, Y., Yamada, K., Yoshikawa, N., Nakamura, K., Haginaka, J., and Kunitomo, M. Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci 11-25-2006;79(26):2474-2479. View abstract.
  • Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006;34:577-82. View abstract.
  • Hattori K, Sukenobu N, Sasaki T, et al. Activation of insulin receptors by lagerstroemin. J Pharmacol Sci 2003;93:69-73. View abstract.
  • Hayashi T, Maruyama H, Kasai R, et al. Ellagitannins from Lagerstroemia speciosa as activators of glucose transport in fat cells. Planta Med 2002;68:173-5. View abstract.
  • Judy WV, Hari SP, Stogsdill WW, et al. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol 2003;87:115-7. View abstract.
  • Kakuda T, Sakane I, Takihara T, et al. Hypoglycemic effect of extracts from Lagerstroemia speciosa L. leaves in genetically diabetic KK-AY mice. Biosci Biotechnol Biochem 1996;60:204-8. View abstract.
  • Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89.View abstract.
  • Miura T, Takagi S, Ishida T. Management of Diabetes and Its Complications with Banaba (Lagerstroemia speciosa L.) and Corosolic Acid. Evid Based Complement Alternat Med. 2012;2012:871495. View abstract.
  • Suzuki Y, Unno T, Ushitani M, et al. Antiobesity activity of extracts from Lagerstroemia speciosa L. leaves on female KK-Ay mice. J Nutr Sci Vitaminol (Tokyo) 1999;45:791-5. View abstract.
  • Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Complement Integr Med. 2016;13(4):413-20.View abstract.
  • Unno T, Sugimoto A, Kakuda T. Xanthine oxidase inhibitors from the leaves of Lagerstroemia speciosa (L.) Pers. J Ethnopharmacol 2004;93:391-5. View abstract.

More Resources for BANABA

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

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© Therapeutic Research Faculty 2018.