SALACIA

OTHER NAME(S):

Chundan, Kathala Hibutu Tea, Ponkoranti, SO, S. oblonga, Salacia oblonga, Salacia reticulata.<br/><br/>

Overview

Overview Information

Salacia is an herb that is native to India and Sri Lanka. The root and stem are used to make medicine.

Salacia has a long history of use as a treatment for diabetes in Ayurveda, traditional Indian medicine. Mugs made from salacia wood are used by people with diabetes to drink water.

In addition to treating diabetes, salacia is used for treating gonorrhea, asthma, itchiness, joint pain (rheumatism), obesity, thirst, and menstrual problems.

How does it work?

Chemicals in salacia seem to prevent sugars in food from being absorbed by the body.

Uses

Uses & Effectiveness?

Possibly Effective for

  • Diabetes. Early research suggests that consuming salacia tea with each meal might lower hemoglobin A1C (HbA1C) levels in people with type 2 diabetes. HbA1C is a measure of blood sugar control. A single dose of salacia, in combination with a meal, also seems to reduce after-meal insulin levels and reduce after-meal blood sugar in healthy volunteers and in people with type 2 diabetes. These reductions indicate better blood sugar control. Other early research suggests that taking salacia with food for 6 weeks seems to reduce pre-meal blood sugar and HbA1C levels in patients with type 2 diabetes.

Insufficient Evidence for

More evidence is needed to rate the effectiveness of salacia for these uses.

Side Effects

Side Effects & Safety

Salacia is POSSIBLY SAFE when taken by mouth, short-term. Single doses of salacia can be consumed safely in doses up to 1000 mg. Consuming salacia tea with food seems to be safe for most people for up to three months. There isn't enough information to know if salacia is safe when used for long periods of time.

Salacia can cause uncomfortable side effects such as gas, belching, pain in the abdomen, nausea, and diarrhea in some people.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking salacia if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Diabetes: Salacia can decrease blood sugar levels. Your diabetes medications might need to be adjusted by your healthcare provider.

Surgery: Salacia might lower blood sugar levels. There is some concern that it might interfere with blood sugar control during and after surgery. Stop using salacia at least 2 weeks before a scheduled surgery.

Interactions

Interactions?

Moderate Interaction

Be cautious with this combination

!
  • Medications for diabetes (Antidiabetes drugs) interacts with SALACIA

    Salacia might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking salacia along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.<br><nb>Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Dosing

Dosing

The appropriate dose of salacia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for salacia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

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  • Huang TH, Yang Q, Harada M, et al. Salacia oblonga root improves cardiac lipid metabolism in Zucker diabetic fatty rats: Modulation of cardiac PPAR-alpha-mediated transcription of fatty acid metabolic genes. Toxicol Appl Pharmacol 2006;210:78-85. View abstract.
  • Ismail TS, Gopalakrishnan S, Begum VH, Elango V. Anti-inflammatory activity of Salacia oblonga Wall. and Azima tetracantha Lam. J Ethnopharmacol 1997;56:145-52. View abstract.
  • Jayawardena MH, de Alwis NM, Hettigoda V, Fernando DJ. A double blind randomised placebo controlled cross over study of a herbal preparation containing Salacia reticulata in the treatment of type 2 diabetes. J Ethnopharmacol 2005;97:215-8. View abstract.
  • Li Y, Peng G, Li Q, et al. Salacia oblonga improves cardiac fibrosis and inhibits postprandial hyperglycemia in obese Zucker rats. Life Sci 2004;75:1735-46. View abstract.
  • Matsuda H, Morikawa T, Masayuki Y. Antidiabetogenic constituents from several natural medicines. Pure Appl Chem 2002;74:1301-8.
  • Matsuda H, Murakami T, Yashiro K, et al. Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate. Chem Pharm Bull (Tokyo) 1999;47:1725-9. View abstract.
  • Matsuda H, Murakami T, Yashiro K, et al. Antidiabetic principles of natural medicines. IV. Aldose reductase and qlpha-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): structure of a new friedelane-type triterpene, kotalagenin 16-acetate. Chem Pharm Bull (Tokyo) 1999;47:1725-9. View abstract.
  • Ratnasooriya WD, Jayakody JR, Premakumara GA. Adverse pregnancy outcome in rats following exposure to a Salacia reticulata (Celastraceae) root extract. Braz J Med Biol Res 2003;36:931-5. View abstract.
  • Williams JA, Choe YS, Noss MJ, et al. Extract of Salacia oblonga lowers acute glycemia in patients with type 2 diabetes. Am J Clin Nutr 2007;86:124-30. View abstract.
  • Wolf BW, Weisbrode SE. Safety evaluation of an extract from Salacia oblonga. Food Chem Toxicol 2003;41:867-74. View abstract.
  • Yoshikawa M, Ninomiya K, Shimoda H, et al. Hepatoprotective and antioxidative properties of Salacia reticulata: preventive effects of phenolic constituents on CCl4-induced liver injury in mice. Biol Pharm Bull 2002;25:72-6. View abstract.
  • Yoshikawa M, Nishida N, Shimoda H, et al. [Polyphenol constituents from Salacia species: quantitative analysis of mangiferin with alpha-glucosidase and aldose reductase inhibitory activities]. Yakugaku Zasshi 2001;121:371-8. View abstract.
  • Yoshikawa M, Shimoda H, Nishida N, et al. Salacia reticulata and its polyphenolic constituents with lipase inhibitory and lipolytic activities have mild antiobesity effects in rats. J Nutr 2002;132:1819-24. View abstract.

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