7-ALPHA-HYDROXY-DHEA

OTHER NAME(S):

3-beta-7-alpha-dihydroxy-5-androstene-17-one, 7a-Hydroxy-Dehydroepiandrosterone, 7-Alfa-Hidroxi-DHEA, 7-Alpha-Hydroxy-Dehydroepiandrosterone, 7-Alpha-Hydroxy-DHEA, 7-Alpha-OH-DHEA, 7-Hydroxy-Dehydroepiandrosterone, 7-Hydroxy DHEA, 7-OH-DHEA.<br/><br/>

Overview

Overview Information

7-alpha-hydroxy-DHEA is a by-product of dehydroepiandrosterone (DHEA) that is formed in the body. DHEA is a “parent” hormone produced by glands near the kidneys.

People take 7-alpha-hydroxy-DHEA to lose weight, increase lean body mass and muscle, boost the immune system, improve memory, and prevent aging.

How does it work?

There is interest in using 7-alpha-hydroxy-DHEA to prevent aging because levels of this substance drop with age. Some people think replacing it might promote youthfulness. 7-alpha-hydroxy-DHEA might also stimulate the immune system and might act like an antioxidant.

Uses

Uses & Effectiveness?

Insufficient Evidence for

  • Promoting weight loss.
  • Increasing lean body mass.
  • Building muscle.
  • Boosting the activity of the immune system.
  • Improving memory.
  • Preventing aging.
  • Other conditions.
More evidence is needed to rate the effectiveness of 7-alpha-hydroxy-DHEA for these uses.

Side Effects

Side Effects & Safety

There isn't enough information available to know if 7-alpha-hydroxy-DHEA is safe or what the possible side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of 7-alpha-hydroxy-DHEA during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Interactions

Interactions?

We currently have no information for 7-ALPHA-HYDROXY-DHEA Interactions.

Dosing

Dosing

The appropriate dose of 7-alpha-hydroxy-DHEA depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for 7-alpha-hydroxy-DHEA. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

View References

REFERENCES:

  • Attal-Khemis S, Dalmeyda V, Michot JL, et al. Increased total 7 alpha-hydroxy-dehydroepiandrosterone in serum of patients with Alzheimer's disease. J Gerontol A Biol Sci Med Sci 1998;53:B125-32. View abstract.
  • Bicikova M, Ripova D, Hill M, et al. Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia. Clin Chem Lab Med 2004;42:518-24. View abstract.
  • Hampl R, Morfin R, Starka L. Minireview 7-hydroxylated derivatives of dehydroepiandrosterone: what are they good for? Endocr Regul 1997;31:211-8. View abstract.
  • Morfin R, Lafaye P, Cotillon AC, et al. 7 alpha-hydroxy-dehydroepiandrosterone and immune response. Ann N Y Acad Sci 2000;917:971-82. View abstract.
  • Pelissier MA, Trap C, Malewiak MI, Morfin R. Antioxidant effects of dehydroepiandrosterone and 7alpha-hydroxy-dehydroepiandrosterone in the rat colon, intestine and liver. Steroids 2004;69:137-44. View abstract.
  • Skinner SJ, Couch RA, Thambyah S, et al. The relationship of plasma 7 alpha-hydroxy dehydroepiandrosterone to disease stage and adrenal androgens in breast cancer patients. Eur J Cancer 1980;16:223-8. View abstract.
  • Starka L, Hampl R, Hanus M, et al. Plasma levels of 7-hydroxymetabolites of dehydroepiandrosterone in healthy Central European aging men. Clin Chem Lab Med 2005;43:1218-22. View abstract.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2018.